Results 141 to 150 of about 10,934,305 (297)

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Non-equilibrium phase transition at a critical point of human blood. [PDF]

Sci Rep, 2021
Pietruszka MA.
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Experimental research on critical point hypothesis

, 2004
According to the critical point hypothesis (CPH), energy release would accelerate in power law before occurrence of large earthquakes or failure of brittle materials.
Yu HZ(余怀忠), Xu ZY(许昭永), Xia MF(夏蒙棼), Liang NG(梁乃刚), Li M(李敏), Peng KY(彭克银), Yin XC(尹祥础)   +6 more
core   +2 more sources

Prevention of COVID-19 transmission from deceased subject: A critical point of view. [PDF]

J Glob Health, 2022
Mele F, Santoro V, Sablone S, Logrado D, Berterame C, Calvano M, Leonardelli M, Macorano E, Duma S, Introna MG, Introna F, De Donno A.   +11 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Dissipative Phase Transition in Systems with Two-Photon Drive and Nonlinear Dissipation near the Critical Point. [PDF]

Nanomaterials (Basel), 2022
Mylnikov VY, Potashin SO, Sokolovskii GS, Averkiev NS.   +3 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Ready or not, here we come: framing nutrition prescribing rights and responsibilities

The South African Journal of Clinical Nutrition
Lauren T Hill
doaj   +1 more source

Critical exponents values for fluids and linear scaled equation of state

Littera Scripta, 2011
The behavior of substance in the vicinity of a critical point is the focus of great scientific interest. A liquid-liquid phase transition in the supercooled region could influence biochemical or precipitation processes. It is interesting that water in a
Radim Mareš, Jana Kalová
doaj