Results 151 to 160 of about 2,430,844 (266)

Micro-CT in ophthalmology: ex vivo preparation and contrasting methods for detailed 3D-visualization of eye anatomy with special emphasis on critical point drying. [PDF]

Quant Imaging Med Surg, 2022
Runge J, Stahnke T, Guthoff RF, Wree A, Keiler J.   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Poincaré-Bendixson Theorem: from Poincaré to the XXIst century

Open Mathematics, 2012
Ciesielski Krzysztof
doaj   +1 more source

Infection curves on small-world networks are linear only in the vicinity of the critical point. [PDF]

Proc Natl Acad Sci U S A, 2021
Kuśmierz Ł, Toyoizumi T.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

A global dataset of remote sensing-based soil critical point and permanent wilting point. [PDF]

Sci Data
Xu Y, He Q, Lu H, Yang K, Entekhabi D, Short Gianotti DJ.   +5 more
europepmc   +1 more source

Critical Point-Finding Methods Reveal Gradient-Flat Regions of Deep Network Losses. [PDF]

Neural Comput, 2021
Frye CG, Simon J, Wadia NS, Ligeralde A, DeWeese MR, Bouchard KE.   +5 more
europepmc   +1 more source

Critical Points [PDF]

Nature, 1972
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Enhanced Superconductivity near the Pressure-Tuned Quantum Critical Point of Charge-Density-Wave Order in Cu_1-δTe (δ = 0.016). [PDF]

Materials (Basel)
Kim KT, Sur Y, Choi I, Wang Z, Kim S, Bhoi D, Kim DY, Kim KH.   +7 more
europepmc   +1 more source