Results 131 to 140 of about 11,033,430 (362)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Multiple positive solutions to a fourth-order boundary-value problem

open access: yesElectronic Journal of Differential Equations, 2016
We study the existence, localization and multiplicity of positive solutions for a nonlinear fourth-order two-point boundary value problem. The approach is based on critical point theorems in conical shells, Krasnoselskii's compression-expansion ...
Alberto Cabada   +3 more
doaj  

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Numerical calculation for limit values of control parameters in the problem about extension with torsion for special sample in the framed structure

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2011
The numerical procedure for computation of the loads limit values was considered in this article. This loads apply to discrete gradient mechanical systems. Part of their elements can work at loss of strength stadium already.
Valeriy V Struzhanov   +1 more
doaj  

Direct measurement of the evolution of magnetism and superconductivity toward the quantum critical point. [PDF]

open access: yesProc Natl Acad Sci U S A, 2022
Higemoto W   +5 more
europepmc   +1 more source

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