Results 141 to 150 of about 16,818,507 (390)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Universality versus nonuniversality in asymmetric fluid criticality

Condensed Matter Physics, 2013
Critical phenomena in real fluids demonstrate a combination of universal features caused by the divergence of long-range fluctuations of density and nonuniversal (system-dependent) features associated with specific intermolecular interactions ...
M.A. Anisimov
doaj   +1 more source

Critical point for membrane bilayer formation. [PDF]

Biochim Biophys Acta Biomembr, 2023
Gershfeld NL, Nossal R.
europepmc   +1 more source

Critical Opalescence around the QCD Critical Point and Second-order Relativistic Hydrodynamic Equations Compatible with Boltzmann Equation [PDF]

, 2009
Teiji Kunihiro, Yuki Minami, Kyosuke Tsumura   +2 more
openalex   +1 more source

Phase structure and critical point in heavy-quark QCD at finite temperature [PDF]

, 2023
K. Kanaya, Ryo Ashikawa, Shinji Ejiri, Masakiyo Kitazawa, Hiroshi Suzuki, Naoki Wakabayashi   +5 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Pseudo-Gap Phase, the Quantum-Critical Point and superconductivity in Copper-Oxide Metals [PDF]

, 1999
C. M. Varma
openalex   +1 more source

Point-of-care ultrasonography for risk stratification of non-critical suspected COVID-19 patients on admission (POCUSCO): A prospective binational study

, 2023
François Morin, Delphine Douillet, Jean François Hamel, Dominique Savary, Christophe Aubé, Karim Tazarourte, Kamélia Marouf, Florence Dupriez, Phillipe Le Conte, Thomas Flament, Thomas A. Delomas, Mehdi Taalba, Nicolas Marjanovic, Françis Couturaud, Nicolas Peschanski, Thomas Boishardy, Jérémie Riou, Vincent Dubée, Pierre‐Marie Roy   +18 more
openalex   +1 more source

Author Correction: A critical review of point-of-use drinking water treatment in the United States [PDF]

, 2022
Jishan Wu, Miao Cao, Draco Tong, Zach Finkelstein, Eric M.V. Hoek   +4 more
openalex   +1 more source