Results 141 to 150 of about 7,571,221 (346)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The breakdown of both strange metal and superconducting states at a pressure-induced quantum critical point in iron-pnictide superconductors. [PDF]

open access: yesNat Commun, 2023
Cai S   +13 more
europepmc   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Pure nematic quantum critical point accompanied by a superconducting dome. [PDF]

open access: yesProc Natl Acad Sci U S A, 2022
Ishida K   +10 more
europepmc   +1 more source

High-speed observation of the piston effect near the gas-liquid critical point [PDF]

open access: green, 2006
Yuichi Miura   +8 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Critical Point-of-care Ultrasound Diagnosis of Fournier's Gangrene: A Case Report. [PDF]

open access: yesClin Pract Cases Emerg Med, 2022
Ramm L   +4 more
europepmc   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Existence of multiple solutions to elliptic problems of Kirchhoff type with critical exponential growth

open access: yesElectronic Journal of Differential Equations, 2014
In this article, we study elliptic problems of Kirchhoff type in dimension $ N \geq 2$, whose nonlinear term has a critical exponential growth. Using variational tools, we establish the existence of at least two nontrivial and nonnegative solutions.
Sami Aouaoui
doaj  

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