Results 91 to 100 of about 847,794 (302)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Elucidation of the Nano-Mechanical Property Evolution of 3D-Printed Zirconia

open access: yesMicro
Understanding the mechanical properties of three-dimensional (3D)-printed ceramics while keeping the parts intact is crucial for advancing their application in high-performance and biocompatible fields, such as biomedical and aerospace engineering.
Joshua Z. R. Dantzler   +8 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Pneumatic dispensing of aqueous Al₂O₃ suspensions via material extrusion additive manufacturing

open access: yesNext Materials
Material extrusion, also known as Robocasting or Direct Ink Writing (DIW) is an efficient and eco-friendly additive manufacturing method for fabricating large and thick ceramic components, such as alumina.
Flavie Lebas   +5 more
doaj   +1 more source

Premium Monovision versus Bilateral Myopic Monovision, Hybrid Monovision and Bilateral Trifocal Implantation: A Comparative Study

open access: yesClinical Ophthalmology, 2022
Georgios Labiris,1 Eirini-Kanella Panagiotopoulou,1 Asli Perente,1 Panagiota Ntonti,1 Konstantinos Delibasis,2 Ioannis Fotiadis,1 Aristeidis Konstantinidis,1 Doukas Dardabounis1 1Department of Ophthalmology, University Hospital of Alexandroupolis ...
Labiris G   +7 more
doaj  

De Architectura (1599) van Charles De Beste. Het vitruvianisme in de Nederlanden in de zestiende eeuw

open access: yesBulletin KNOB, 1995
An unknown manuscript in the Koninklijke Bibliotheek (Royal Library) of Brussels (ms. II 7617) by the Bruges mason/bricklayer Charles De Beste: Architectura.
Charles van den Heuvel
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Probability distribution of the sizes of largest erased-loops in loop-erased random walks

open access: yes, 2001
We have studied the probability distribution of the perimeter and the area of the k-th largest erased-loop in loop-erased random walks in two-dimensions for k = 1 to 3.
A. Dhar   +24 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy