Results 231 to 240 of about 11,237,275 (282)

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Quality by Design-Driven Formulation Development of Cannabidiol Orally Disintegrating Tablets. [PDF]

open access: yesScientifica (Cairo)
Monton C   +5 more
europepmc   +1 more source

Family Care Management of Patients With Chronic Diseases: A Concept Analysis. [PDF]

open access: yesNurs Open
Maleki RN   +4 more
europepmc   +1 more source

Quality by Design Approach for Understanding the Critical Quality Attributes of Cyclosporine Ophthalmic Emulsion

Molecular Pharmaceutics, 2014
Restasis is an ophthalmic cyclosporine emulsion used for the treatment of dry eye syndrome. There are no generic products for this product, probably because of the limitations on establishing in vivo bioequivalence methods and lack of alternative in vitro bioequivalence testing methods.
Ziyaur Rahman, Xiaoming Xu, Mansoor Khan
exaly   +3 more sources

Determination of critical quality attributes for monoclonal antibodies using quality by design principles

Biologicals, 2016
Quality by design (QbD) is a global regulatory initiative with the goal of enhancing pharmaceutical development through the proactive design of pharmaceutical manufacturing process and controls to consistently deliver the intended performance of the product.
Thomas Emrich   +2 more
exaly   +3 more sources

Impact of critical process parameters and critical material attributes on the critical quality attributes of liposomal formulations prepared using continuous processing

International Journal of Pharmaceutics, 2022
Liposomes were one of the earliest drug delivery vehicles used for anti-cancer therapeutics and similarly, lipid-based nanoparticles have been used for abundance of applications as gene therapies. The methods to produce these particles have remained relatively unchanged until the recent emergence of continuous manufacturing.
Gowtham Yenduri   +3 more
openaire   +2 more sources

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