Results 261 to 270 of about 11,237,275 (282)

Revisiting MSC expansion from critical quality attributes to critical culture process parameters

Process Biochemistry, 2017
Abstract With over 300 clinical trials registered in 2013 and more than 20,000 hits on the NCBI database, human multipotent stromal cells (hMSC) are widely used and studied as a model for tissue engineering and regenerative medicine. This review aims to provide a general update on the latest advances regarding hMSC characterization and bioprocessing.
Céline Martin, Éric Olmos, Marie-Laure Collignon, Natalia De Isla, Fabrice Blanchard, Isabelle Chevalot, Annie Marc, Emmanuel Guedon   +7 more
openaire   +1 more source

Data-driven estimation of critical quality attributes on industrial processes

2022
Large data sets generated and stored by continuous monitoring of process variables in process plants enable the development of data-driven mathematical models of a process. While such models do not provide detailed insight into the process, they do provide a feasible description of the nonlinear complex process dynamics.
Ujević Andrijić, Željka, Herceg, Srečko, Bolf, Nenad   +2 more
openaire   +1 more source

Biopharmaceutical Critical Quality Attributes

2023
openaire   +1 more source

[The control of the critical quality attributes of amoxicillin and clavulanate potassium tablet].

Yao xue xue bao = Acta pharmaceutica Sinica, 2018
The critical attribute was analyzed in clavulanate potassium tablet of amoxicillin according to the principle QbD. By investigation of the drug impurity profile, the cycle-closed dimer and penicilloic acid of amoxicillin were considered to be the critical impurities, and the sources and the degradation pathways of these two impurities were discussed ...
Xiao-meng, Chong, Jin, Li, Yan, Wang, Chen, Wang, Li-xin, Wang, Shang-chen, Yao, Chang-qin, Hu   +6 more
openaire   +1 more source

Quality Control Testing, Characterization and Critical Quality Attributes of Adeno-Associated Virus Vectors Used for Human Gene Therapy

Biotechnology Journal, 2021
J Fraser Wright
exaly  

Critical Quality Attributes of Biomass that Affect Downstream Conversion

2023
Onyinye Okonkwo, Chang Dou, James Gardner   +2 more
openaire   +1 more source

Critical Quality Attributes

2018
openaire   +2 more sources

NIR robustness model of variable selection investigation of critical quality attributes coupled with different simulate noises by prediction capability and reproducibility

Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2022
Xiao Song, Xiaona Liu, Mingli Zhu
exaly  

Comment on “Quality by Design Approach for Understanding the Critical Quality Attributes of Cyclosporine Ophthalmic Emulsion”

Molecular Pharmaceutics, 2014
Anuradha, Gore, Mayssa, Attar, Chetan, Pujara, Sesha, Neervannan   +3 more
openaire   +2 more sources

Assessing microstructural critical quality attributes in PLGA microspheres by FIB-SEM analytics

Journal of Controlled Release, 2022
Aiden Zhu
exaly