Results 81 to 90 of about 13,580,142 (270)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Blending Extensive and Intensive Reading to Enhance Critical Reading Skills in The EFL Context

Journal of Languages and Language Teaching
This study explores the integration of extensive and intensive reading strategies and their impact on critical reading and critical thinking skills in an English as a Foreign Language (EFL) context.
Hamzah Puadi Ilyas, Istaryatiningtias Istaryatiningtias   +1 more
doaj   +1 more source

Critical reading for critical engagement with English literature: a critical reflective study

Perspectives in Education, 2013
In South African secondary schools, critical reading is encouraged by the CAPS policy document, but still some learners, even at university level, find it difficult to utilise critical reading, a skill that is believed by scholars to promote critical ...
John Simango
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Critical Reading of Ghazali's Perspective on the Destiny of Man by Himself [PDF]

Journal of Philosophical Investigations
Explaining the extent of human influence on existence and his role in determining and changing his destiny is one of the most important theological topics that has always been the focus of thinkers and scholars of various schools of Islamic philosophy ...
Faranak Bahmani, Ali Hosseini
doaj   +1 more source

Vocabulary Coverage and Size in EFL Critical Reading [PDF]

Research on the relationship between vocabulary knowledge and reading has largely focused on literal comprehension of informational texts. The present study, however, investigates the vocabulary-reading relationship by specifically examining critical ...
Brahim Ait Hammou,Abderrazak Zaafour,Nadif Bendaoud ,Mohammed Zemrani
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Relationship between critical thinking dispositions and critical reading skills of Malaysian ESL learners

, 2014
Critical thinking disposition, an inclination (Facione, Facione & Giancarlo, 2000) or tendency (Stunipsky, Renaud, Daniels, Haynes & Perry 2008) to use critical thinking skills, is one of the essential components in critical thinking.
Wong, Bee Eng, Mohd Zin, Zuhana
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source