Results 91 to 100 of about 13,580,142 (270)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A framework to build readers and writers in the second language classroom
Colombian Applied Linguistics Journal, 2003 This article proposes a framework to create readers and writers in the second language classroom. The components of the framework are curriculum, instruction and assessment.
Gilma Zúñiga Camacho
doaj +1 more source
The Role of Critical Reading to Promote Students’ Critical Thinking and Reading Comprehension
, 2020 Developing students' critical thinking and reading comprehension is crucial, particularly for those in colleges, because they need to read numerous scientific journals and textbooks written in English.
Syaadiah Arifin
semanticscholar +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The Hidden Foundations of Critical Reading
, 2016 What do we actually know about the reading experiences taking place within literary studies? And what can we know? Despite the growing academic interest in real readers, literary scholars are a category of readers whose reading experiences we know very ...
Persson, Magnus,
core +1 more source
Cendekia: Jurnal Pendidikan dan Pembelajaran, 2018 This study aims to identify the authentic assessment forms used in learning critical reading of texts exposition. In this research, using qualitative methods with this kind of phenomenology.
Arwan Arwan
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Incorporating Environmental Education in English Language Teaching through Bloom’s Revised Taxonomy
Selçuk Üniversitesi Edebiyat Fakültesi Dergisi, 2018 It has become undeniable that language learners should be aware of global problems. One of the most serious problems of our globe today is the environmental degradation and education practices should have a contribution to ecological conservation ...
Defne Erdem Mete
doaj +1 more source