Results 61 to 70 of about 344,156 (288)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
FANTASTIC FICTION ON THE PAGES OF FYODOR DOSTOEVSKY'S LITERARY WORKS [PDF]
Проблемы исторической поэтики, 2008 The article presents critical analysis of Fyodor Dostoevsky's "fantastic" realism concept, and gives reasons for defining Dostoevsky’s artistic method as Christian realism.
Zakharov V. N.
doaj
Critical Realism: The Epistemic Position of Gestalt Theoretical Psychotherapy
Gestalt Theory, 2021 In this contribution, I discuss the relevance of epistemological models for psychotherapy. Despite its importance epistemology is seldom explicitly dealt with in the psychotherapeutic landscape.
Sternek Katharina
doaj +1 more source
The “Positive Argument” for Constructive Empiricism and Inference to the Best Explanation [PDF]
, 2018 In this paper, I argue that the “positive argument” for Constructive Empiricism (CE), according to which CE “makes better sense of science, and of scientific activity, than realism does” (van Fraassen 1980, 73), is an Inference to the Best Explanation ...
Mizrahi, Moti
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
, 2014 State of the art paper on the topic realism/anti-realism. The first part of the paper elucidates the notions of existence and independence of the metaphysical characterization of the realism/anti-realism dispute.
Castro, Eduardo
core +1 more source
Historical inductions, Old and New [PDF]
, 2015 I review prominent historical arguments against scientific realism to indicate how they display a systematic overshooting in the conclusions drawn from the historical evidence.
A Bird +26 more
core +3 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
‘A realist theory of art history’. Review of: Ian Verstegen, A Realist Theory of Art History (Ontological Explorations), London and New York: Routledge 2013 [PDF]
Journal of Art Historiography, 2013 Until recently, art history has been dominated by anti-realist and social-constructivist ideologies—arguably, in a more radical form than this has been the case in other fields of the humanities. Ian Verstegen’s book A Realist theory of Art History is an
Branko Mitrović
doaj
Oil Imag(e)inaries: Critical Realism and the Oil Sands
Imaginations: Journal of Cross-Cultural Media Studies, 2012 eng
Imre Szeman, Maria Whiteman
doaj +1 more source