Results 71 to 80 of about 5,968,098 (330)
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Theoretical Procedures and Elder-Vass's Critical Realist Ontology [PDF]
, 2012 This article scrutinizes some theoretical procedures prevalent in the philosophy of social science. These procedures are exemplified in Elder-Vass’s critical realism, which promises to place the social sciences on a sound ontological footing. The article
Archer M. +7 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Complex realism, applied social science and postdisciplinarity: a critical assessment of the work of David Byrne [PDF]
, 2014 In this review essay I offer a critical assessment of the work of David Byrne, an applied social scientist who is one of the leading advocates of the use of complexity theory in the social sciences and who has drawn on the principles of critical realism ...
Holland, D
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
BJPsych BulletinIn this opinion article, we discuss the application of critical realism as an alternative model to the biopsychosocial model in the understanding of psychiatric disorders.
Mohammed Al Alawi +2 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Fallibilism and Ontology in Tuukka Kaidesoja’s Critical Realist Social Ontology
Journal of Social Ontology, 2015 This article addresses Tuukka Kaidesoja’s critique of the philosophical presuppositions of Roy Bhaskar’s theories of critical realism. The article supports Kaidesoja’s naturalistic approach to the philosophy of the social sciences, including the field ...
Daniel Little
doaj +2 more sources
Five potentials of critical realism in management and organization studies
, 2020 There is a lack of research explicitly demonstrating the potential of applying critical realism in qualitative empirical Management and Organization Studies (MOS).
Dennis J. Frederiksen, L. Kringelum
semanticscholar +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source