Results 81 to 90 of about 5,968,098 (330)

Critical Realism

open access: yes, 2012
Critical realism has become increasingly well known in the social sciences, particularly for its trenchant critiques of forms of idealism such as positivism and interpretivism. Rarely, however, has critical realism itself been subjected to critique. This article argues that realism and idealism are just two sides of the same foundationalist coin, with ...
openaire   +2 more sources

Critical Realism: The Epistemic Position of Gestalt Theoretical Psychotherapy

open access: yesGestalt Theory, 2021
In this contribution, I discuss the relevance of epistemological models for psychotherapy. Despite its importance epistemology is seldom explicitly dealt with in the psychotherapeutic landscape.
Sternek Katharina
doaj   +1 more source

Aesthetics and literature : a problematic relation? [PDF]

open access: yes, 2007
The paper argues that there is a proper place for literature within aesthetics but that care must be taken in identifying just what the relation is. In characterising aesthetic pleasure associated with literature it is all too easy to fall into reductive
F. Kermode   +23 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Topological correction of hypertextured implicit surfaces for ray casting [PDF]

open access: yes, 2007
Hypertextures are a useful modelling tool in that they can add three-dimensional detail to the surface of otherwise smooth objects. Hypertextures can be rendered as implicit surfaces, resulting in objects with a complex but well defined boundary ...
Gamito, M.N., Maddock, S.C.
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

FANTASTIC FICTION ON THE PAGES OF FYODOR DOSTOEVSKY'S LITERARY WORKS [PDF]

open access: yesПроблемы исторической поэтики, 2008
The article presents critical analysis of Fyodor Dostoevsky's "fantastic" realism concept, and gives reasons for defining Dostoevsky’s artistic method as Christian realism.
Zakharov V. N.
doaj  

The “Positive Argument” for Constructive Empiricism and Inference to the Best Explanation [PDF]

open access: yes, 2018
In this paper, I argue that the “positive argument” for Constructive Empiricism (CE), according to which CE “makes better sense of science, and of scientific activity, than realism does” (van Fraassen 1980, 73), is an Inference to the Best Explanation ...
Mizrahi, Moti
core   +1 more source

Opportunity, discovery and creativity : a critical realist perspective [PDF]

open access: yes, 2014
In this article, we draw upon the philosophy of critical realism to reflect upon issues concerning discovery processes and opportunity development. First, paradoxes in the relationship between opportunity discovery and creativity are identified and ...
Martin, Lee, Wilson, N. R.
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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