Results 91 to 100 of about 6,950,475 (283)

Thermal and structural modeling of superinsulation [PDF]

open access: yes, 1971
Model permits direct physical measurement of the thermal response of critical components of space telescopes, thus providing flexibility for systems studies and design ...
Marshall, K. N.   +2 more
core   +1 more source

Critical behaviour in the nonlinear elastic response of hydrogels

open access: yes, 2016
In this paper we study the elastic response of synthetic hydrogels to an applied shear stress. The hydrogels studied here have previously been shown to mimic the behaviour of biopolymer networks when they are sufficiently far above the gel point. We show
Dennison, M.   +5 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Triage implementation in resource-limited emergency departments: sharing tools and experience from the Pacific region

open access: yesInternational Journal of Emergency Medicine
According to the World Health Organization’s (WHO) Emergency Care Systems Framework, triage is an essential function of emergency departments (EDs). This practice innovation article describes four strategies that have been used to support implementation ...
Rob Mitchell   +5 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Response to Critics

open access: yesJournal for the History of Analytical Philosophy, 2019
All contributions included in the present issue were originally prepared for an “Author Meets Critics” session organized by Carl Sachs for the Eastern Division Meeting of the American Philosophical Association in Savannah, Georgia, on 5th January, 2018.
openaire   +4 more sources

Case Report: Successful avoidance of etoposide for primary hemophagocytic lymphohistiocytosis-induced multiple organ dysfunction syndrome using emapalumab

open access: yesFrontiers in Pediatrics
We describe the case of an infant who presented with simple rhinovirus/enterovirus bronchiolitis whose condition worsened with rapid progression to multiple organ dysfunction syndrome (MODS).
Timothy J. Hahn   +8 more
doaj   +1 more source

Frozen Disorder in a Driven System

open access: yes, 1996
We investigate the effects of quenched disorder on the universal properties of a randomly driven Ising lattice gas. The Hamiltonian fixed point of the pure system becomes unstable in the presence of a quenched local bias, giving rise to a new fixed point
A. Aharony   +30 more
core   +1 more source

Home - About - Disclaimer - Privacy