Results 91 to 100 of about 6,939,801 (335)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Triage implementation in resource-limited emergency departments: sharing tools and experience from the Pacific region

International Journal of Emergency Medicine
According to the World Health Organization’s (WHO) Emergency Care Systems Framework, triage is an essential function of emergency departments (EDs). This practice innovation article describes four strategies that have been used to support implementation ...
Rob Mitchell, Libby White, Leigh Elton, Cliff Luke, Sarah Bornstein, Vincent Atua   +5 more
doaj   +1 more source

Frozen Disorder in a Driven System

, 1996
We investigate the effects of quenched disorder on the universal properties of a randomly driven Ising lattice gas. The Hamiltonian fixed point of the pure system becomes unstable in the presence of a quenched local bias, giving rise to a new fixed point
A. Aharony, A. Aharony, A. Aharony, A. B. Harris, A. D. Bruce, A. I. Larkin, A. P. Young, B. I. Halperin, B. I. Halperin, B. Schmittmann, B. Schmittmann, B. Schmittmann, B. Schmittmann, C. de Dominicis, C. Maes, E. Brézin, E. Praestgaard, G. Grinstein, G. Parisi, H. K. Janssen, J. W. Perram, J. Zinn-Justin, K. E. Bassler, P. C. Hohenberg, P. C. Martin, P. L. Garrido, R. B. Stinchcombe, R. Kubo, S. Katz, V. Becker, Z. Cheng   +30 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Impacts and implications of heat exposure in the Australian workplaces

Safety and Health at Work, 2022
Matt Brearley
doaj   +1 more source

Low Field Magnetic Response of the Granular Superconductor LaSrCuO

, 1997
The properties of the low excitation field magnetic response of the granular high temperature (HTSC) superconductor LaSrCuO have been analyzed at low temperatures. The response of the Josephson currents has been extracted from the data.
Feigel'man, M. V., Gurevich, L. A., Leylekian, L., Ocio, M.   +3 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Case Report: Successful avoidance of etoposide for primary hemophagocytic lymphohistiocytosis-induced multiple organ dysfunction syndrome using emapalumab

Frontiers in Pediatrics
We describe the case of an infant who presented with simple rhinovirus/enterovirus bronchiolitis whose condition worsened with rapid progression to multiple organ dysfunction syndrome (MODS).
Timothy J. Hahn, Timothy J. Hahn, Daniel J. McKeone, Daniel J. McKeone, James W. Beal, Jessica E. Ericson, Jessica E. Ericson, E. Scott Halstead, E. Scott Halstead   +8 more
doaj   +1 more source

On the theory of diamagnetism in granular superconductors

, 1994
We study a highly disordered network of superconducting granules linked by weak Josephson junctions in magnetic field and develop a mean field theory for this problem.
C. Ebner, D. A. Huse, G. Blatter, L. B. Ioffe, L. B. Ioffe, M. Freixa-Pascual, M. J. P. Gingras, M. V. Feigel'man, M. V. Feigelman, V. M. Vinokur   +9 more
core   +2 more sources