Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Alcohol - related violence among Australian Aboriginal and Torres Strait Islanders (also called as "Indigenous") is a major public health concern in Northern Territory of Australia.
Ramya Ramamoorthi +3 more
doaj
Response-A Critical Response to "Discourse Communities and the Discourse of Experience". [PDF]
Macneill P.
europepmc +1 more source
Excitonic Effects in Two-Dimensional Massless Dirac Fermions
We study excitonic effects in two-dimensional massless Dirac fermions with Coulomb interactions by solving the ladder approximation to the Bethe-Salpeter equation. It is found that the general 4-leg vertex has a power law behavior with the exponent going
Brey, L. +3 more
core +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Reading Response in Mary Balogh: A Critical Engagement
A long established author of Regency-set romances, Mary Balogh has a history of subverting the trends and tropes of the genre. This paper examines how Balogh uses subversion as a form of participating in the critical discussion on romance novels that ...
Veera Mäkelä
doaj
Critical Response to Article "Network Pharmacology and Experimental Validation to Explore the Effect and Mechanism of Kanglaite Injection Against Triple-Negative Breast Cancer" [Letter]. [PDF]
Dany F, Nikmah UA, Lienggonegoro LA.
europepmc +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Another potential etiology for cardiac manifestation after snakebite
This letter discusses the possibility of Takotsubo cardiomyopathy (TTC) as an alternative diagnosis in a recently reported case of acute myocardial infarction following a hump-nosed viper bite.
Yoshihiro Aoki +2 more
doaj +1 more source
Critical Response to Article "Integrated Network Pharmacology and Experimental Validation Approach to Investigate the Mechanisms of Stigmasterol in the Treatment of Rheumatoid Arthritis" [Letter]. [PDF]
Rinendyaputri R, Panjaitan NSD.
europepmc +1 more source

