Results 141 to 150 of about 3,824,363 (314)

Critical editing of Music and Interpretation. Critical Editions for critical Musicians?

open access: yes, 2006
The article discusses the relationship between historical-critical editions of music and historically informed performance ...
Urchueguía, Cristina
core  

Resilience and Protection of Critical Information Infrastructure Resilience and Protection of Critical Information Infrastructure

open access: yes, 2018
The article deals with resilience and protection of critical information infrastructure elements. The elements affect rapid recovery of the system to its original state and the increase of resistance during the subsequent emergency events.
Petr Hruza
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Critical success factors in ERP implementation: A review

open access: yes, 2008
ERP systems have become vital strategic tools in today’s competitive business environment. This ongoing research study presents a review of recent research work in ERP systems.
Al-Salti, Z, Al-Fawaz, K, Eldabi, T
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The ghost in the system: Critical management studies in Turkey

open access: yes, 2016
Critical Management Studies (CMS) did not find a place and could not establish itself in Turkish business schools. This is not a new claim; it has been argued by extant research.
Gençer, M., Oba, B.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On The Two Dimensional Gierer-Meinhardt system with strong coupling

open access: yes, 1999
We construct solutions with a single interior condensation point for the two-dimensional Gierer-Meinhardt system with strong coupling. The condensation point is located at a nondegenerate critical point of the diagonal part of the regular part
Winter, M   +3 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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