Results 81 to 90 of about 3,824,363 (314)
Feasibility of Xenogeneic Mitochondrial Transplantation in Neuronal Systems: An Exploratory Study
LifeMitochondrial transplantation (MTx) has emerged as a potential therapeutic approach for diseases associated with mitochondrial dysfunction, yet its scalability and cross-species feasibility remain underexplored.
Eriko Nakamura +8 more
doaj +1 more source
Bacterial Topography of the Healthy Human Lower Respiratory Tract
mBio, 2017 Although culture-independent techniques have refuted lung sterility in health, controversy about contamination during bronchoscope passage through the upper respiratory tract (URT) has impeded research progress.
Robert P. Dickson +6 more
doaj +1 more source
On critical semilinear elliptic systems
Advances in Differential Equations, 2001 The goal of the present paper is to study the existence of solutions of the semilinear elliptic system \[ \begin{gathered} -\Delta u+ u= |v|^{q-1} v+ g(x,v)\quad\text{in }\mathbb{R}^n,\\ -\Delta v+ v= |u|^{p-1} u+ f(x,u)\quad\text{in }\mathbb{R}^N,\\ u(x)\to 0\text{ and }v(x)\to 0\quad \text{as }|x|\to \infty,\end{gathered}\tag{1} \] where \({1\over p ...
openaire +3 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Critical Theory -- An Alternative Solution to IT Planning Implementation Problems in Tourism [PDF]
, 2004 Empirical evidence is presented, which suggests that current approaches to IT in tourism are dominated by the assumptions of the Postpositivist paradigm and are failing to meet the objectives they have set for themselves.
Philip Alford, Alford, Philip
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
On the Fault Hypothesis for a Safety-Critical Real-Time System
, 2004 A safety-critical real-time computer system must provide its services with a dependability that is much better than the dependability of any one of its constituent components.
Kopetz, Hermann
core
, 2010 PURPOSE OF REVIEW: Critical incident reporting alone does not necessarily improve patient safety or even patient outcomes. Substantial improvement has been made by focusing on the further two steps of critical incident monitoring, that is, the analysis ...
David Schwappach +3 more
core +1 more source
Acute lung injury and post-cardiac arrest syndrome: a narrative review
Journal of Intensive CareBackground Post-cardiac arrest syndrome (PCAS) presents a multifaceted challenge in clinical practice, characterized by severe neurological injury and high mortality rates despite advancements in management strategies.
Yusuke Endo +9 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source