Results 61 to 70 of about 9,373,330 (295)

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Therapeutic potential of mitochondrial transplantation in modulating immune responses post-cardiac arrest: a narrative review

Journal of Translational Medicine
Background Mitochondrial transplantation (MTx) has emerged as a novel therapeutic strategy, particularly effective in diseases characterized by mitochondrial dysfunction.
Tomoaki Aoki, Yusuke Endo, Eriko Nakamura, Cyrus E. Kuschner, Jacob Kazmi, Parmeshar Singh, Tai Yin, Lance B. Becker, Kei Hayashida   +8 more
doaj   +1 more source

Real‐world use of inhaled treprostinil for lung disease‐pulmonary hypertension: A protocol for patient evaluation and prescribing

Pulmonary Circulation, 2022
Inhaled treprostinil was approved recently for interstitial lung disease‐pulmonary hypertension; however, efficacy in “real‐world” populations is not known.
Shelsey W. Johnson, Lauren Finlay, Stephen C. Mathai, Ronald H. Goldstein, Bradley A. Maron   +4 more
doaj   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

Critical Systems Librarianship [PDF]

, 2018
In this chapter we perform a meta-analysis and synthesize existing critical library and information studies work into a cohesive approach to critical systems librarianship, informed by diverse perspectives and ethical lenses. We seek to enable and facilitate a critically-informed, reflective, and reflexive approach to systems work with specific focus ...
Barron, Simon, Preater, Andrew, Nicholson, Karen P., Seale, Maura   +3 more
openaire   +4 more sources

Identification and management of incidental findings in a Veteran’s lung cancer screening program

Respiratory Research
Background Incidental findings (IFs) are common on low dose CT obtained during lung cancer screening (LCS). The identification and management of clinically significant IFs is a challenging aspect of LCS programs and there is no standardized method of ...
Renee L. Colucci, Eric Garshick, Julie White, Emily S. Wan, Julianne O’Leary, Lisa A. Blake, Samantha M. Hoyt, Demerise Johnston, Kathleen LaCerda, Michelle Morreale-Karl, Anupma Jati, Fatima G. Wilder, Daniel C. Wiener, Justin M. Rucci, Ronald H. Goldstein   +14 more
doaj   +1 more source

Serum bilirubin and the risk of chronic obstructive pulmonary disease exacerbations

Respiratory Research, 2017
Background Bilirubin is a potent anti-oxidant and higher serum concentrations of bilirubin have been associated with better lung function, slower lung function decline, and lower incidence of chronic obstructive pulmonary disease (COPD).
Kirstin E. Brown, Don D. Sin, Helen Voelker, John E. Connett, Dennis E. Niewoehner, Ken M. Kunisaki, for the COPD Clinical Research Network   +6 more
doaj   +1 more source

Program computes single-point failures in critical system designs [PDF]

, 1967
Computer program analyzes the designs of critical systems that will either prove the design is free of single-point failures or detect each member of the population of single-point failures inherent in a system design.
Brown, W. R.
core   +1 more source

Interplay of quantum and classical fluctuations near quantum critical points

, 2011
For a system near a quantum critical point (QCP), above its lower critical dimension $d_L$, there is in general a critical line of second order phase transitions that separates the broken symmetry phase at finite temperatures from the disordered phase ...
A Paduan-Filho, A Saguia, AA Aczel, AJ Millis, AL Fetter, AP Young, BA Jones, D Reyes, D-X Yao, F Evers, H Caldas, HV Löhneysen, J Flouquet, JA Hertz, JC Guillou Le, JC Guillou Le, KG Wilson, KG Wilson, L Yin, LS Goldner, M Hasenbusch, MA Continentino, MA Continentino, MA Continentino, MA Continentino, MA Continentino, MA Continentino, MA Continentino, MA Continentino, MA Continentino, MA Continentino, Mucio Amado Continentino, P Pfeuty, PF Bedaque, Q Si, R Jullien, R Reisser, RR Santos dos, S Sachdev, S Sachdev, T Moriya, T Moriya, VS Zapf, W Janke, Y Kohama   +44 more
core   +1 more source