Results 91 to 100 of about 11,241,667 (250)

Six methods to determine expiratory time constants in mechanically ventilated patients: a prospective observational physiology study

Intensive Care Medicine Experimental
Background Expiratory time constant (τ) objectively assesses the speed of exhalation and can guide adjustments of the respiratory rate and the I:E ratio with the goal of achieving complete exhalation.
Filip Depta, Caitlyn M. Chiofolo, Nicolas W. Chbat, Neil R. Euliano, Michael A. Gentile, Dušan Rybár, Viliam Donič, Marko Zdravkovic   +7 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Review of Counter-terrorism technologies. A critical assessment

, 2020
Book Review of Counter-terrorism technologies. A critical assessmentby Peter Lehr, Cham, Switzerland: Springer International Publishing, 2019, 217 pp., £79.99 (hardback), ISBN: 978-3-319-90923-
Hacsek, Zsófia; id_orcid
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

NEW TECHNOLOGIES AND CRITICAL LITERACY: ideas for activities in an English classroom [PDF]

, 2015
The aim of this article is to suggest different ways to use new technologies, mainly the internet, in an English teaching environment based on some Critical Literacy principles.
Lopes, Izabela Cristina Teixeira, Neves, Aline Cristina Monteiro, Costa Leite, Patrícia Mara de Carvalho   +2 more
core   +1 more source

Biogas Upgrading and Bottling Technologies: A Critical Review

Energies
Biogas upgrading and bottling represent essential processes in transforming raw biogas produced via the anaerobic digestion of organic waste into high-purity biomethane (≥95% CH4), a renewable energy source suitable for applications in cooking ...
Yolanda Mapantsela, Patrick Mukumba
doaj   +1 more source

Critical Material Applications and Intensities in Clean Energy Technologies

, 2019
Clean energy technologies have been developed to address the pressing global issue of climate change; however, the functionality of many of these technologies relies on materials that are considered critical.
Gabrielle Gaustad, Alexandra Leader
core   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Analyzing the differences and correlations between key metabolites and dominant microorganisms in different regions of Daqu based on off-target metabolomics and high-throughput sequencing

Heliyon
Daqu is usually produced in an open environment, which makes its quality unstable. The microbial community of Daqu largely determines its quality. Therefore, in order to improve the fermentation characteristics of Daqu, samples were collected from Jinsha
Yijie Dai, Lei Yu, Jintao Ao, Rui Wang
doaj   +1 more source