Results 91 to 100 of about 3,567,823 (296)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Prediction of Critical Temperatures [PDF]

open access: yesNature, 1957
IN cases where critical temperatures are unknown they can be calculated from a number of empirical or semi-empirical formulae1, the simplest but least-accurate being Guldberg's rule. More accurate equations exist for estimating values for hydrocarbons, for example, those of Jatkar and Lakshminarayanan2 and Watson3, but these are unsuitable for use with
D. K. H. BRIGGS, W. D. DRAKE
openaire   +1 more source

Nonequilibrium Critical Phenomena

open access: yes, 2000
We discuss the non-equilibrium critical phenomena in liquids, and the models for these phenomena based on local equilibrium and extended scaling assumptions. Special situations are proposed for experimental tests of the theory.
Alexander Patashinski   +20 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Enhancing the critical temperature of strained Niobium films

open access: yesMaterials Research Express, 2020
The study of the high critical temperature ( T _c ) of hydrogen compounds under high pressure has resulted in a considerable focus on Bardeen–Cooper–Schrieffer superconductors.
Joonyoung Choi   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Self-energy and critical temperature of weakly interacting bosons

open access: yes, 2003
Using the exact renormalization group we calculate the momentum-dependent self-energy Sigma (k) at zero frequency of weakly interacting bosons at the critical temperature T_c of Bose-Einstein condensation in dimensions 3 k_c, where Sigma (k) propto k^{2
J. O. Andersen   +8 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Phase Structure of QED3 at Finite Temperature

open access: yes, 1992
Dynamical symmetry breaking in three-dimensional QED with N fermion flavours is considered at finite temperature, in the large $N$ approximation. Using an approximate treatment of the Schwinger-Dyson equation for the fermion self-energy, we find that ...
Appelquist   +22 more
core   +1 more source

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