Results 81 to 90 of about 3,567,823 (296)

The Ising Spin Glass in dimension four

open access: yes, 2015
The critical behaviors of the bimodal and Gaussian Ising spin glass (ISG) models in dimension four are studied through extensive numerical simulations, and from an analysis of high temperature series expansion (HTSE) data of Klein {\it et al.} (1991 ...
Campbell, I. A., Lundow, P. H.
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Critical temperature of antikaon condensation in nuclear matter

open access: yes, 2008
We investigate the critical temperature of Bose-Einstein condensation of $K^-$ mesons in neutron star matter. This is studied within the framework of relativistic field theoretical models at finite temperature where nucleon-nucleon and (anti)kaon-nucleon
Bandyopadhyay, Debades   +2 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The Effect of Oxygen Limitation on a Xylophagous Insect’s Heat Tolerance Is Influenced by Life-Stage Through Variation in Aerobic Scope and Respiratory Anatomy

open access: yesFrontiers in Physiology, 2019
Temperature has a profound impact on insect fitness and performance via metabolic, enzymatic or chemical reaction rate effects. However, oxygen availability can interact with these thermal responses in complex and often poorly understood ways, especially
Marion Javal   +9 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Investigation of Finite-Size 2D Ising Model with a Noisy Matrix of Spin-Spin Interactions

open access: yesEntropy, 2018
We analyze changes in the thermodynamic properties of a spin system when it passes from the classical two-dimensional Ising model to the spin glass model, where spin-spin interactions are random in their values and signs. Formally, the transition reduces
Boris Kryzhanovsky   +2 more
doaj   +1 more source

Frequency-domain study of relaxation in a spin glass model for the structural glass transition

open access: yes, 2003
We have computed the time-dependent susceptibility for the finite-size mean-field Random Orthogonal model (ROM). We find that for temperatures above the mode-coupling temperature the imaginary part of the susceptibility $\chi''(\nu)$ obeys the scaling ...
A Crisanti   +19 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Temperature-induced topological phase transition in HgTe quantum wells

open access: yes, 2018
We report a direct observation of temperature-induced topological phase transition between trivial and topological insulator in HgTe quantum well.
Consejo, C.   +11 more
core   +2 more sources

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