Results 101 to 110 of about 3,567,823 (296)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Geometric Aspects and Some Uses of Deformed Models of Thermostatistics
Universe, 2018 We consider diverse deformed Bose gas models (DBGMs) focusing on distributions and correlations of any order, and also on deformed thermodynamics. For so-called μ -deformed Bose gas model ( μ -DBGM), main thermodynamic aspects are treated: total
Alexandre Gavrilik
doaj +1 more source
Casimir force in the O(n -> infinity) model with free boundary conditions
, 2014 We present results for the temperature behavior of the Casimir force for a system with a film geometry with thickness $L$ subject to free boundary conditions and described by the $n\to\infty$ limit of the $O(n)$ model.
Bergknoff, Jonathan +2 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Temperature-enhanced critical quantum metrology
Physical Review AWe show that the performance of critical quantum metrology protocols, counter-intuitively, can be enhanced by finite temperature. We consider a toy-model squeezing Hamiltonian, the Lipkin-Meshkov-Glick model and the paradigmatic Ising model. We show that the temperature enhancement of the quantum Fisher information can be achieved by adiabatic ...
Laurin Ostermann, Karol Gietka
openaire +2 more sources
Effects of temperature on thick branes and the fermion (quasi-)localization
, 2011 Following Campos's work [Phys. Rev. Lett. 88, 141602 (2002)], we investigate the effects of temperature on flat, de Sitter (dS), and anti-de Following Campos's work [Phys. Rev. Lett.
A Campos +87 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Quantum entanglement in the neighborhood of pseudo-transition for a spin-1/2 Ising-XYZ diamond chain
, 2018 Recently has been observed for some one-dimensional models that exhibit unexpected pseudo-transitions and quasi-phases. This pseudo-transition resembles a first- and second-order phase transition simultaneously.
Carvalho, I. M. +4 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source