Results 91 to 100 of about 4,838,264 (300)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Quantum critical response: from conformal perturbation theory to holography

, 2017
We discuss dynamical response functions near quantum critical points, allowing for both a finite temperature and detuning by a relevant operator. When the quantum critical point is described by a conformal field theory (CFT), conformal perturbation ...
Lucas, Andrew, Sierens, Todd, Witczak-Krempa, William   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

D-branes and SQCD in Non-Critical Superstring Theory

, 2005
Using exact boundary conformal field theory methods we analyze the D-brane physics of a specific four-dimensional non-critical superstring theory which involves the N=2 SL(2)/U(1) Kazama-Suzuki model at level 1.
A. Fotopoulos, A. Fotopoulos, A. Giveon, A. Giveon, A. Hanany, A.B. Zamolodchikov, Angelos Fotopoulos, B. Gato-Rivera, B. Ponsot, C. Ahn, D. Israel, D. Kutasov, D. Kutasov, D. Kutasov, J. Teschner, K. Hori, K. Hosomichi, M. Alishahiha, M. Dörrzapf, M.R. Gaberdiel, Nikolaos Prezas, O. Aharony, O. Aharony, P. Di Vecchia, P. Di Vecchia, S. Elitzur, S. Kuperstein, S. Mizoguchi, S. Murthy, S. Ribault, T. Eguchi, T. Eguchi, T. Eguchi, V. Fateev, V.A. Fateev, Vasilis Niarchos   +35 more
core   +5 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Komodifikasi Upacara Religi Dalam Pemasaran Pariwisata

Jurnal Aspikom, 2011
Development of tourism program is basically done as an effort to support income sources. Policy of tourism is a key factor in its. Facts showed that the policy has not been fully align ed to the local societies. Commodification of religious ceremony is
Dhyah Ayu Retno Widyastuti
doaj   +1 more source

Bad or worse? Applying critical theory to explore the impacts of Payatas dumpsite closure on the former waste pickers. [PDF]

Waste Manag Res, 2023
Ito H, Igano C.
europepmc   +1 more source

Femme‐toring: Leveraging critical femininities and femme theory to cultivate alternative approaches to mentoring [PDF]

, 2023
Rhea Ashley Hoskin, Lilith A. Whiley
openalex   +1 more source

Quantum State Density and Critical Temperature in M-theory

, 2001
We discuss the asymptotic properties of quantum states density for fundamental $p-$branes which can yield a microscopic interpretation of the thermodynamic quantities in M-theory.
A. A. BYTSENKO, B. M. PIMENTEL, Bytsenko A. A., M. C. B. ABDALLA, Meinardus G.   +4 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source