Results 81 to 90 of about 613,818 (299)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Critical Theory or Accepted Practice? Combining Careers in Critical Care Medicine and Gastroenterology. [PDF]

Dig Dis Sci, 2022
Saffo S, Leventhal TM.
europepmc   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

‘A Few Practical Things’: The Redress of Law and the Irritation of (Critical) Constitutional Theory

, 2023
Angelo Golia
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Qu’est-ce que la critique dans la philosophie critique de la race ?

Astérion
The article takes the notion of critique seriously in order to evaluate to what extent, according to what characterisations, under what conditions, and with what limits critical philosophy of race (CPR), which refers to critical race theory specifically ...
Magali Bessone
doaj   +1 more source

Metapresentiality: a foundational concept for a critical theory of digital health. [PDF]

Salud Colect, 2023
Almeida Filho N.
europepmc   +1 more source

6 Towards a Critical Theory of Democracy: Participatory Democracy and Social Freedom [PDF]

, 2019
Brian Caterino, Phillip Hansen
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Treatment Patterns and Triple Therapy Utilization in Chinese Patients with Chronic Obstructive Pulmonary Disease: An Analysis of Real-World Data from the Yinzhou Database

International Journal of COPD
Yan Chen,1 Xinli Li,2 Dongni Hou,3 Wenhao Li,4 Zhike Liu,4 Meng Zhang,4 IokFai Cheang,2 Peng Shen,5 Hongbo Lin,5 Siyan Zhan,4 Feng Sun,4 Yuanlin Song3,6– 8 1Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital of Central South ...
Chen Y, Li X, Hou D, Li W, Liu Z, Zhang M, Cheang I, Shen P, Lin H, Zhan S, Sun F, Song Y   +11 more
doaj