Results 71 to 80 of about 5,200,298 (246)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
A Critical Perspective to Critical Thinking
Florence Nightingale Journal of Nursing, 2019 Critical thinking is a higly valued skill today not only in academic settings, especially in higher education, but also in professional enviroments. Employers expect individuals who think critically; teachers want students who think critically; society ...
Hülya Kaya
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Saber & Educar, 2015 Recognizing the importance of developing critical thinking of students research has been developed in order to establish answer to the question of how to promote this kind of thinking.
Rui Marques Vieira +1 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
A comparison of critical thinking skills for hospitality management graduates from associate and baccalaureate degree programs [PDF]
, 2001 Plan BIt has been suggested that the university and college hospitality management programs must change their programs to meet the needs of the industry.
Oliver, Michael J.
core
Critical thinking for engineers and engineering critical thinking [PDF]
2016 2nd International Conference of the Portuguese Society for Engineering Education (CISPEE), 2016 (Design decisions for a critical thinking curriculum for Engineering students serves as a point of departure to briefly describe an under-appreciated reason to emphasize critical thinking in Engineering programs. An increasing focus on the role of context, environment and systems in shaping human judgement means that engineers should be especially ...
openaire +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
, 2017 With the recognition of the importance of teaching critical inquiry within the Ontario Elementary school language curriculum, this study explores how teachers put these expectations into practice.
Carlson, Heather
core