Results 71 to 80 of about 5,549,552 (344)

TRANSFUSION TRIGGERS IN CRITICALLY ILL PATIENTS

open access: yesPakistan Armed Forces Medical Journal, 2019
Objective: To determine the frequency of inappropriate transfusions in tertiary care hospital. Study Design: Cross sectional study. Place and Duration of Study: General Intensive Care Unit (ICU) Lady Reading Hospital Peshawar, from Dec 2017 to Feb ...
Aisha Kulsoom Mufti
doaj  

Pain and dyspnea control during awake fiberoptic bronchoscopy in critically ill patients: safety and efficacy of remifentanil target-controlled infusion [PDF]

open access: gold, 2021
Margot Caron   +15 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

The significance of RDW and LDH in pediatric critical illness

open access: yesEgyptian Pediatric Association Gazette
Background The LDH level, which can be easily assessed, was described to be independently associated with in-hospital mortality. Also, independent of illness severity in critically ill children, red cells distribution width (RDW)was associated with ...
Radwa Iraqy   +4 more
doaj   +1 more source

Bloodstream infections in critically ill patients with COVID‐19

open access: yesEuropean Journal of Clinical Investigation, 2020
Little is known about the incidence and risk of intensive care unit (ICU)‐acquired bloodstream infections (BSI) in critically ill patients with coronavirus disease 2019 (COVID‐19).
D. Giacobbe   +21 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Lung Microbiota Predict Clinical Outcomes in Critically Ill Patients.

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2020
RATIONALE Recent studies have revealed that in critically ill patients, lung microbiota are altered and correlate with alveolar inflammation. The clinical significance of altered lung bacteria in critical illness is unknown.
R. Dickson   +10 more
semanticscholar   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

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