Results 81 to 90 of about 5,549,552 (344)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo +9 morewiley +1 more sourceClinical characteristics and day-90 outcomes of 4244 critically ill adults with COVID-19: a prospective cohort study
Intensive Care Medicine, 2020 Purpose To describe acute respiratory distress syndrome (ARDS) severity, ventilation management, and the outcomes of ICU patients with laboratory-confirmed COVID-19 and to determine risk factors of 90-day mortality post-ICU admission.Matthieu David Alexandre Tài Alain Martin Said Antoine Alai Schmidt Hajage Demoule Pham Combes Dres Lebbah Kim, M. Schmidt, D. Hajage, A. Demoule, T. Pham, A. Combes, M. Dres, S. Lebbah, A. Kimmoun, A. Mercat, G. Béduneau, Jessica Palmyre, Margot Prevost, P. Asfar, François M. Beloncle, J. Demiselle, A. Pavot, X. Monnet, C. Richard, J. Mayaux, A. Beurton, Richard Descamps, A. Joret, D. du Cheyron, F. Pène, J. Chiche, M. Jozwiak, P. Jaubert, G. Voiriot, M. Fartoukh, Marion Teulier, C. Blayau, E. L'her, C. Aubron, L. Bodénes, N. Ferrière, J. Auchabie, Anthony Le Meur, Sylvain Pignal, Thierry Mazzoni, J. Quenot, P. Andreu, Jean-Baptiste Roudau, Marie Labruyere, S. Nseir, S. Préau, J. Poissy, D. Mathieu, S. Benhamida, R. Paulet, Nicolas Roucaud, M. Thyrault, F. Daviet, S. Hraiech, Gabriel Parzy, A. Sylvestre, S. Jochmans, Anne-Laure Bouilland, M. Monchi, Marc Danguy des Déserts, Q. Mathais, G. Rager, P. Pasquier, Reignier Jean, Seguin Amélie, Garret Charlotte, Canet Emmanuel, J. Dellamonica, Clément Saccheri, R. Lombardi, Yanis Kouchit, S. Jacquier, A. Mathonnet, Mai-Anh Nay, I. Runge, F. Martino, L. Flurin, Amélie Rollé, M. Carles, R. Coudroy, A. Thille, J. Frat, Maeva Rodriguez, P. Beuret, A. Tientcheu, Arthur Vincent, Florian Michelin, M. Melone, Maxime Gauzi, A. Guilbert, G. Kouadri, V. Gissot, S. Ehrmann, C. Salmon-Gandonnière, Djlali Elaroussi, A. Delbove, Y. Fédun, J. Huntzinger, E. Lebas, G. Kisoka, C. Grégoire, S. Marchetta, B. Lambermont, L. Argaud, T. Baudry, Pierre-jean Bertrand, A. Dargent, C. Guitton, Nicolas Chudeau, M. Landais, C. Darreau, A. Ferré, A. Gros, G. Lacave, F. Bruneel, M. Neuville, J. Devaquet, G. Tachon, Richard Gallot, R. Chelha, A. Galbois, A. Jallot, L. Lemoine, K. Kuteifan, Valentin Pointurier, L. Jandeaux, J. Mootien, C. Damoisel, B. Sztrymf, J. Chommeloux, C. Luyt, F. Schortgen, Leon Rusel, C. Jung, F. Gobert, D. Vimpére, L. Lamhaut, B. Sauneuf, Liliane Charrier, Julien Calus, Isabelle Desmeules, B. Painvin, J. Tadié, V. Castelain, B. Michard, Jean-Etienne Herbrecht, M. Baldacini, N. Weiss, S. Demeret, C. Marois, B. Rohaut, P. Moury, Anne-Charlotte Savida, E. Couadau, M. Série, N. Alexandru, C. Bruel, Candice Fontaine, S. Garrigou, Juliette Courtiade Mahler, Maxime Leclerc, M. Ramakers, P. Garçon, Nicole Massou, Ly van Vong, J. Sen, Nolwenn Lucas, F. Chemouni, A. Stoclin, A. Avenel, H. Faure, Angélie Gentilhomme, S. Ricôme, Paul Abraham, C. Monard, J. Textoris, T. Rimmele, Florent Montini, G. Lejour, T. Lazard, I. Etienney, Y. Kerroumi, D. Claire, Bereiziat Marine Coupez, Thouy François, Clémet Hoffmann, N. Donat, V. Muller, Thibault Martinez, Audrey Jacquot, Matthieu Mattei, Bruno Lévy, Ramin Ravan, Loïc Dopeux, Jean-Mathias Liteaudon, D. Roux, Brice Rey, R. Anghel, Déborah Schenesse, Vincent Gevrey, Jermy Castanera, P. Petua, B. Madeux, O. Hartman, M. Piagnerelli, Anne Joosten, C. Noel, P. Biston, Thibaut Noel, G. Bouar, Messabi Boukhanza, Elizabeth J. Demarest, Marie-France Bajolet, N. Charrier, A. Quenet, C. Zylberfajn, N. Dufour, B. Mégarbane, S. Voicu, N. Deye, I. Malissin, F. Legay, M. Debarre, Nicolas Barbarot, P. Fillâtre, Bertrand Delord, Thomas Laterrade, T. Saghi, Wilfried Pujol, P. Cungi, P. Esnault, M. Cardinale, V. Hong Tuan Ha, Grégory Fleury, Marie-Ange Brou, Daniel Zafimahazo, D. Tran-Van, P. Avargues, Lisa Carenco, Nicolas Robin, A. Ouali, Lucie Houdou, C. Le Terrier, N. Suh, S. Primmaz, J. Pugin, E. Weiss, T. Gauss, J. Moyer, C. Paugam‐Burtz, B. La Combe, Rolland Smonig, Jade Violleau, Pauline Cailliez, J. Chelly, A. Marchalot, Cécile Saladin, C. Bigot, P. Fayolle, J. Fatséas, Amr Ibrahim, D. Résière, R. Hage, C. Cholet, Marie Cantier, P. Trouiller, P. Montravers, B. Lortat-Jacob, Sébastien Tanaka, Alexy Tran-Dinh, J. Duranteau, A. Harrois, G. Dubreuil, Marie Werner, A. Godier, S. Hamada, D. Zlotnik, H. Nougué, A. Mekontso-Dessap, G. Carteaux, K. Razazi, N. de Prost, N. Mongardon, O. Langeron, E. Levesque, A. Attias, C. de Roquetaillade, B. Chousterman, A. Mebazaa, E. Gayat, M. Garnier, E. Pardo, L. Satre-Buisson, C. Gutton, Élise Yvin, C. Marcault, É. Azoulay, M. Darmon, Nicolas J. Bonnet, N. Ebstein, S. Gaudry, Y. Cohen, H. Ait-Oufella, Geoffroy Hariri, T. Urbina, Sandie Mazerand, Nicholas Heming, F. Santi, P. Moine, D. Annane, Adrien Bouglé, Edris Omar, Aymeric Lancelot, E. Begot, G. Plantefeve, D. Contou, H. Mentec, O. Pajot, S. Faguer, O. Cointault, L. Lavayssière, M. Nogier, M. Jamme, C. Pichereau, J. Hayon, H. Outin, F. Dépret, M. Coutrot, M. Chaussard, L. Guillemet, P. Goffin, Romain Thouny, J. Guntz, Laurent Jadot, R. Persichini, V. Jean-Michel, H. Georges, T. Caulier, Gael Pradel, M. Hausermann, ThiMy Hue Nguyen-Valat, Michel Boudinaud, Emmanuel Vivier, Sylvène Rosseli, G. Bourdin, C. Pommier, M. Vinclair, S. Poignant, S. Mons, W. Bougouin, F. Bruna, Quentin Maestraggi, Christian Roth, L. Bitker, François Dhelft, Justine Bonnet-Chateau, Mathilde Filippelli, Tristan Morichau-Beauchant, S. Thierry, C. Le Roy, Mélanie Saint Jouan, B. Gonçalves, Aurélien Mazeraud, M. Daniel, T. Sharshar, Cyril Cadoz, Rostane Gaci, S. Gette, G. Louis, Sophe-Caroline Sacleux, Marie-Amélie Ordan, A. Cravoisy, M. Conrad, Guilhem Courte, S. Gibot, Y. Benzidi, C. Casella, L. Serpin, Jean-Lou Setti, Marie-Catherine Besse, A. Bourreau, J. Pillot, C. Rivera, Camille Vinclair, M. Robaux, Chloé Achino, M. Delignette, Tessa Mazard, F. Aubrun, B. Bouchet, A. Frerou, L. Muller, C. Quentin, Samuel Degoul, Xavier Stihle, Claude Sumian, N. Bergero, Bernard Lanaspre, H. Quintard, E. Maiziere, P. Egreteau, G. Leloup, F. Berteau, M. Cottrel, M. Bouteloup, M. Jeannot, Q. Blanc, J. Saison, Isabelle Geneau, R. Grenot, Abdel Ouchike, P. Hazera, Anne-Lyse Masse, S. Demiri, C. Vézinet, Ėlodie Baron, D. Benchetrit, A. Monsel, G. Trebbia, E. Schaack, R. Lepecq, M. Bobet, C. Vinsonneau, Thibault Dekeyser, Quentin Delforge, I. Rahmani, Bérengère Vivet, Jonathan Paillot, Lucie Hierle, C. Chaignat, S. Valette, B. Her, Jennifier Brunet, M. Page, F. Boiste, Anthony Collin, Florent Bavozet, Aude Garin, Mohamed Dlala, K. Mhamdi, Bassem Beilouny, Alexandra Lavalard, Severine Perez, B. Veber, P. Guitard, P. Gouin, Anna Lamacz, F. Plouvier, Bertrand P. Delaborde, A. Kherchache, Amina Chaalal, J. Ricard, M. Amouretti, S. Freita-Ramos, D. Roux, J. Constantin, M. Assefi, Marine Lecore, Agathe Selves, F. Prevost, C. Lamer, Ruiying Shi, L. Knani, S. Pili-Floury, L. Vettoretti, M. Levy, L. Marsac, S. Dauger, S. Guilmin-Crépon, Jean-Baptiste Putegnat, F. Bayle, Maya Perrou, Ghyslaine Thao, G. Geri, C. Charron, X. Repéssé, A. Vieillard-Baron, M. Guilbart, Pierre-Alexandre Roger, Sébastien Hinard, Pierre-Yves Macq, K. Chaulier, S. Goutte, P. Chillet, A. Pitta, Barbara Darjent, A. Bruneau, S. Lasocki, M. Léger, Soizic Gergaud, P. Lemarié, N. Terzi, C. Schwebel, Anais Dartevel, L. Galerneau, J. Diehl, C. Hauw‐Berlemont, N. Péron, E. Guérot, A. Amoli +499 moresemanticscholar +1 more sourceMechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira +3 morewiley +1 more sourceDependency in Critically Ill Patients
Global Qualitative Nursing Research, 2016 By necessity, critically ill patients admitted to intensive care units (ICUs) have a high level of dependency, which is linked to a variety of negative feelings, such as powerlessness.Rumei Yangdoaj +1 more source