Results 171 to 180 of about 1,231,981 (407)

Letter: Exploring the clinical utility of ammonia in critically ill patients with cirrhosis: More to do? [PDF]

, 2023
Jiajia Dong, Qiongying Zhang, Yi‐Jing Cai   +2 more
openalex   +1 more source

Characteristics and Outcomes of 21 Critically Ill Patients with COVID-19 in Washington State

Journal of Emergency Medicine, 2020
C. Eastin, T. Eastin
semanticscholar   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Strokes in Critically Ill COVID-19 Patients Diagnosed After Deep Sedation: A Single-Center Case Series [PDF]

, 2023
Gwen G. Garrido-Bagayo, Jo Ann R Soliven
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Percutaneous cholecystostomy: a nonsurgical therapeutic option for acute cholecystitis in high-risk and critically ill patients

São Paulo Medical Journal
Percutaneous cholecystostomy offers a potentially important type of therapy for critically ill patients with acute cholecystitis who present high risk when undergoing laparotomy or laparoscopy under general anesthesia.
Guilherme de Castro Dabus, Sérgio San Juan Dertkigil, Jamal Baracat   +2 more
doaj   +1 more source

Rectal swabs in critically-ill patients provide discordant representations of the gut microbiome compared to stool samples: a brief methodologic report [PDF]

, 2019
Katherine Fair, D.G. Dunlap, Adam Fitch, Alison Morris, Bryan J. McVerry, Georgios D. Kitsios   +5 more
openalex   +1 more source

Clinical Characteristics of Critically Ill Patients Infected with COVID-19 in Rasoul Akram Hospital in Iran: A Single Center Study [PDF]

, 2020
Poupak Rahimzadeh, Saied Amniati, Reza Farahmandrad, Seyed Hamid Reza Faiz, Setareh Hedayati Emami, Azadeh Habibi   +5 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Leucocytosis in critically ill patients is not always a sign of infection! [PDF]

, 2002
Gabriel Izbicki, Bernard Rudensky, Mira Naamad, Moshe Hersch   +3 more
openalex   +1 more source