Results 81 to 90 of about 1,231,981 (407)

COVID-19 is associated with distinct myopathic features in the diaphragm of critically ill patients

BMJ Open Respiratory Research, 2021
Introduction The diaphragm is the main muscle of inspiration, and its dysfunction contributes to adverse clinical outcomes in critically ill patients. We recently reported the infiltration of SARS-CoV-2, and the development of fibrosis, in the diaphragm ...
Zhonghua Shi, Leo Heunks, Marianna Bugiani, Sylvia J P Bogaards, Stefan Conijn, Yeszamin Onderwater, Pedro Espinosa, Diewertje I Bink, Marloes van den Berg, Martijn van de Locht, Hans van der Hoeven, Reinier A Boon, Coen A C Ottenheijm   +12 more
doaj   +1 more source

Clearance of Lormetazepam, Midazolam, and Their Conjugated Metabolites by Continuous Venovenous Hemofiltration During Prolonged Sedation in Critically Ill Patients With COVID‐19‐Associated Acute Respiratory Distress Syndrome [PDF]

, 2021
Kimberly N. Shudofsky, Paddy K.C. Janssen, Norbert A. Foudraine, Jos L.M.L. le Noble   +3 more
openalex   +1 more source

Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults

Critical Care Medicine, 2019
Objective: Decades-old, common ICU practices including deep sedation, immobilization, and limited family access are being challenged. We endeavoured to evaluate the relationship between ABCDEF bundle performance and patient-centered outcomes in critical ...
B. Pun, Michele C Balas, Mary Ann Barnes-Daly, Jennifer L. Thompson, J. R. Aldrich, J. Barr, Diane G. Byrum, S. Carson, J. Devlin, Heidi J. Engel, C. Esbrook, K. Hargett, Lori A. Harmon, Christina Hielsberg, J. Jackson, T. Kelly, Vishakha Kumar, Lawson Millner, Alexandra Morse, C. Perme, Patricia J. Posa, K. Puntillo, W. Schweickert, Joanna L. Stollings, Alai Tan, L. D. McGowan, E. W. Ely   +26 more
semanticscholar   +1 more source

Individualization of piperacillin dosing for critically ill patients: Dosing software to optimize antimicrobial therapy [PDF]

, 2014
Piperacillin-tazobactam is frequently used for empirical and targeted therapy of infections in critically ill patients. Considerable pharmacokinetic (PK) variability is observed in critically ill patients.
Boselli, E., Felton, T. W., Hope, W. W., Lodise, T. P., Neely, M. N., Roberts, J. A., Van Guilder, M.   +6 more
core   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Impact on the work of clinical pharmacist at the pharmacotherapy management of critically ill patient: Local experience in a clinical hospital [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2018
Context: The complexity in critical patient management and polypharmacy, raise the need for support from a clinical pharmacist to optimize drug therapies.
Jorge S. Amador, Ruben A. Hernández, Cristian M. Gutiérrez, José C. Plaza-Plaza   +3 more
doaj  

Electrocardiographic Time-Intervals Waveforms as Potential Predictors for Severe Acute Kidney Injury in Critically Ill Patients [PDF]

, 2023
Francesco Corradi, Gregorio Santori, Claudia Brusasco, Chiara Robba, Adrian Wong, Pierpaolo Di Nicolò, Ludovica Tecchi, Federico Dazzi, Erika Taddei, Alessandro Isirdi, Federico Coccolini, Francesco Forfori, Guido Tavazzi   +12 more
openalex   +1 more source

Covid-19: FDA approves use of convalescent plasma to treat critically ill patients

British medical journal, 2020
The US Food and Drug Administration has approved the use of plasma from recovered patients to treat people who are critically ill with covid-19, provided that doctors get approval over the telephone.1 The method has been used in the past to treat ...
J. Tanne
semanticscholar   +1 more source

Ventilator-associated pneumonia in critically ill patients with COVID-19

Critical Care, 2021
Pandemic COVID-19 caused by the coronavirus SARS-CoV-2 has a high incidence of patients with severe acute respiratory syndrome (SARS). Many of these patients require admission to an intensive care unit (ICU) for invasive ventilation and are at ...
Mailis Maes, E. Higginson, J. Pereira-Dias, M. Curran, S. Parmar, F. Khokhar, Delphine Cuchet-Lourenço, Janine Lux, Sapna Sharma-Hajela, Benjamin Ravenhill, I. Hamed, Laura Heales, R. Mahroof, Amelia T. Soderholm, S. Forrest, S. Sridhar, N. Brown, S. Baker, V. Navapurkar, G. Dougan, Josefin Bartholdson Scott, A. Conway Morris   +21 more
semanticscholar   +1 more source

Delirium management in critically ill patients [PDF]

, 2013
Delirium among critically ill patients is common. Presence of delirium imparts a poorer prognosis to patients, including longer ICU and hospital length of stay, increased risk of institutionalization, higher health related costs, and elevated mortality ...
Calvo-Ayala, Enrique, Khan, Babar
core   +1 more source