Parabens as Agents for Improving Crocetin Esters’ Shelf-Life in Aqueous Saffron Extracts [PDF]
Molecules, 2009 The effect of parabens on the shelf-life of crocetin esters and picrocrocin in aqueous saffron solutions was studied. Degradation of saffron crocetin esters fits a first-order kinetics model, and the results indicated that the crocetin (β-D-glucosyl)-(β ...
Gonzalo L Alonso +1 more
exaly +7 more sources
Effects of Crocetin Esters and Crocetin from Crocus sativus L. on Aortic Contractility in Rat Genetic Hypertension [PDF]
Molecules, 2015 Background: Endothelial dysfunction, characterized by an enhancement in vasoconstriction, is clearly associated with hypertension. Saffron (Crocus sativus L.) bioactive compounds have been recognized to have hypotensive properties.
Silvia Llorens +2 more
exaly +6 more sources
Biotechnological production of crocetin and crocins using a carotenoid cleavage dioxygenase (CCD4) from Nyctanthes arbor-tristis [PDF]
Frontiers in Plant ScienceCrocins are hydrophilic crocetin esters composed of a linear chain with glucose molecules added at the end. Crocins and crocetin are used as cosmetic agents and effective pharmaceuticals for the treatment of several diseases.
Oussama Ahrazem +2 more
exaly +6 more sources
Effect of Crocus sativus L. Stigmas Microwave Dehydration on Picrocrocin, Safranal and Crocetin Esters [PDF]
Foods, 2021 The dehydration process is the basis to obtain high quality saffron and to preserve it for a long time. This process modifies saffron’s main metabolites that define its quality, and are responsible for the characteristic color, taste, and aroma of the ...
Aarón García-Blázquez +4 more
doaj +3 more sources
UHPLC Analysis of Saffron (Crocus sativus L.): Optimization of Separation Using Chemometrics and Detection of Minor Crocetin Esters [PDF]
Molecules, 2018 Ultra-high performance liquid chromatography (UHPLC) coupled with diode array detection (DAD) was applied to improve separation and detection of mono- and bis-glucosyl esters of crocetin (crocins), the main red-colored constituents of saffron (Crocus ...
Angelo Antonio D’Archivio +4 more
doaj +4 more sources
The assembly of tetrameric human L-lactate dehydrogenase is regulated by ionic strength, β-NADH binding, cyclic peptides, and long-chain dicarboxylates. [PDF]
Protein SciAbstract Lactate dehydrogenases catalyze the reduction of pyruvate to lactate, the generation of which is of importance for the energetic metabolism of malignant cells. In particular, human cancer cells overexpress lactate dehydrogenase A (hLDH‐A), whose catalytic activity depends on its assembly into the corresponding homotetramer (denoted as hLDH‐5),
Stefan A +7 more
europepmc +2 more sources
Effects of total daily light integral from blue and broad-band red LEDs on flowering of saffron (Crocus sativus L.) [PDF]
Scientific Reports, 2023 Present indoor cultivation of saffron (Crocus sativus L.) only depends on artificial planting experience, so that flower number and stigma yield are seriously affected in case of cloudy or rainy days and temperature changes.
Dan Gao +7 more
doaj +2 more sources
<i>Crocus sativus</i> (Saffron) Aqueous Extract Mediated Green Synthesis of Iron Oxide Nanoparticles and Their In Vitro and In Vivo Biological Investigations. [PDF]
Food Sci NutrThe Crocus sativus (saffron) aqueous extract mediated green synthesis of iron oxide nanoparticles and their in vitro and in vivo biological investigations. ABSTRACT The present study reports the green synthesis of iron oxide nanoparticles (IONPs) using the aqueous extract of Crocus sativus (saffron) as a natural reducing and stabilizing agent, followed
Rauf A +10 more
europepmc +2 more sources
Bioconversion of carotenoids into high-value crocins using a marine sponge carotenoid cleavage dioxygenase. [PDF]
New PhytolSummary Carotenoids and apocarotenoids are widespread specialized metabolites, yet animals, including sponges, lack the ability to synthesize carotenoids de novo and must obtain them from dietary or microbial sources. The roles of carotenoid cleavage dioxygenases (CCDs) in marine animals remain largely unexplored. A CCD from the marine sponge Suberites
Moreno-Giménez E +11 more
europepmc +2 more sources
Functional, Nutraceutical and Health Endorsing Perspectives of Saffron. [PDF]
Food Sci NutrSaffron is generally regarded as safe for human consumption in moderate quantities, its potential adverse effects at higher doses require careful consideration. This review presents a balanced perspective on saffron's medicinal potential and its safe usage, making it a valuable resource for researchers and healthcare professionals.
Tufail T +4 more
europepmc +2 more sources