Results 1 to 10 of about 1,784 (118)
Protective Effects of Safranal Against Spike Protein-Induced Mitochondrial Dysfunction and Inflammation in Peripheral and Central Immune Cells [PDF]
Current Developments in NutritionBackground: Saffron (Crocus sativus L.) contains bioactive molecules with antioxidant, anti-inflammatory, and neuroprotective properties. Growing evidence indicates that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) promotes ...
Antonella Girgenti +9 more
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Investigation of the Effects of Saffron on Neuroprotection and Circadian Rhythm in an In Vitro Parkinson’s Model [PDF]
PharmaceuticalsBackground/Objectives: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by dopaminergic neuronal loss, oxidative stress, and mitochondrial dysfunction.
Ayse Aksoy +2 more
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Pharmacological effects of Safranal: An updated review [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Safranal (a monoterpene aldehyde) is the major volatile component of saffron which is responsible for the saffron unique odor. Several studies have shown the pharmacological activities of safranal including anti-oxidant, anti-inflammatory ...
Danial Esmaeilzadeh +5 more
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Inhibitory effects of safranal on laser-induced choroidal neovascularization and human choroidal microvascular endothelial cells and related pathways analyzed with transcriptome sequencing [PDF]
International Journal of Ophthalmology, 2021 AIM: To determine the effects of safranal on choroidal neovascularization (CNV) and oxidative stress damage of human choroidal microvascular endothelial cells (HCVECs) and its possible mechanisms. METHODS: Forty-five rats were used as a laser-induced CNV
Qin-Xiao +11 more
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Molecules, 2022 Introduction: Safranal, which endows saffron its unique aroma, causes vasodilatation and has a hypotensive effect in animal studies, but the mechanisms of these effects are unknown.
Noor Nadhim Al-Saigh, Shtaywy Abdalla
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Frontiers in Endocrinology, 2022 AimTo determine the effect of safranal on diabetic retinopathy in vitro and its possible mechanisms.MethodsWe used human retinal microvascular endothelial cells (HRMECs) to test the influence of safranal in vitro.
Qin Xiao +19 more
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Safranal Alleviated OVA-Induced Asthma Model and Inhibits Mast Cell Activation
Frontiers in Immunology, 2021 IntroductionAsthma is a chronic and recurring airway disease, which related to mast cell activation. Many compounds derived from Chinese herbal medicine has promising effects on stabilizing mast cells and decreasing inflammatory mediator production ...
Peeraphong Lertnimitphun +12 more
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Safranal, a saffron constituent, attenuates retinal degeneration in P23H rats. [PDF]
PLoS ONE, 2012 Saffron, an extract from Crocus sativus, has been largely used in traditional medicine for its antiapoptotic and anticarcinogenic properties. In this work, we investigate the effects of safranal, a component of saffron stigmas, in attenuating retinal ...
Laura Fernández-Sánchez +5 more
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Frontiers in Oncology, 2023 IntroductionSafranal is an active component of the traditional Tibetan medicine (TTM) saffron, which has potential anticancer activity.Methods and resultsHere, we studied the therapeutic effect and mechanism of safranal on GBM.
Xiaobing Yang +24 more
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Molecules, 2022 Saffron is a very high value-added ingredient used in the food supplement market and contains a high level of safranal. Adding synthetic safranal to saffron, which is significantly cheaper, and falsifying the origin of saffron may represent recurrent ...
Benjamin Moras +6 more
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