Results 41 to 50 of about 2,346 (204)

Safranal Inhibits Angiogenesis via Targeting HIF-1α/VEGF Machinery: In Vitro and Ex Vivo Insights

open access: yesFrontiers in Oncology, 2022
Nature has a nearly infinite inventory of unexplored phytochemicals and biomolecules that have the potential to treat a variety of diseases. Safranal exhibits anti-cancer property and the present study explores its antiangiogenic property. Hepatocellular
Ali Abdalla   +3 more
doaj   +1 more source

Multi‐Target Mechanisms of Moroccan Aphrodisiac Plants: An Integrative Computational and Phytochemical Investigation

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200 
Amal Elrherabi   +8 more
wiley   +1 more source

The synthesis of safranal [PDF]

open access: yes, 1953
Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1953.MIT copy bound with: Solution and emulsion copolymerization of alkenyl siloxanes with vinyl type monomers / by Earl W.
Nelson, David A. (David Alan), 1931-
core  

Adverse Events of Saffron (Crocus sativus L.): Systematic Review of Current Evidence

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Crocus sativus L., commonly known as saffron, is a widely used spice with a rich history of culinary and medicinal applications. This systematic review aims to compile human data from studies on monopreparations of C. sativus, including stigma powder and other extracts, to evaluate their safety.
Fatemeh Sadat Hasheminasab   +3 more
wiley   +1 more source

Saffron Alters Microbial Amino Acid Metabolism and Neurotransmitter Production in a Defined Gut Consortium

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
Graphical representation of the metabolic pathways modulated by saffron within defined microbial communities. In the tryptophan pathway, saffron decreased levels of tryptophan and anthranilic acid while increasing concentrations of indole‐3‐acetic acid and tryptamine.
Adelaide E. Horvath   +9 more
wiley   +1 more source

Protective effects of safranal against subchronic thinner inhalation induced oxidative stress in rats [PDF]

open access: yes, 2023
339-348In phytotherapy, research on the effects of components in plant extracts on various diseases gets increasing attention. . Saffron is an herb with antioxidant effects, known to have an increasing significance due to its therapeutic effects ...
Sevimli, S   +9 more
core   +1 more source

Evaluation of Lung and Bronchoalveolar Lavage Fluid Oxidative Stress Indices for Assessing the Preventing Effects of Safranal on Respiratory Distress in Diabetic Rats

open access: yesThe Scientific World Journal, 2014
We investigated the effects of antioxidant activity of safranal, a constituent of Crocus sativus L., against lung oxidative damage in diabetic rats. The rats were divided into the following groups of 8 animals each: control, diabetic, and three diabetic +
Saeed Samarghandian   +2 more
doaj   +1 more source

Dietary Bioactives and Physical Activity in the Regulation of Hippocampal Neurogenesis and Cognitive Decline

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
Exercise and dietary polyphenols enhance hippocampal plasticity and cognitive function via complementary molecular mechanisms. Central pathways include BDNF signaling, inflammation control, and mitochondrial regulation. Although synergy is mainly supported by preclinical data, lifestyle‐based strategies show promise for brain health maintenance ...
Zhenyi Zhao, Sima‐sadat Sabihi
wiley   +1 more source

Retinal function in control and safranal-treated P23H rats.

open access: yes, 2012
(A–B) Example of scotopic (A) and photopic (B) ERG traces from a P120 rat treated with vehicle (left) or safranal (right). Units on the left of panels represent the luminance of the flashes in log cd·s/m2.
Nicolás Cuenca (142887)   +5 more
core   +1 more source

The Safranal Effect against Cyclophosphamide-Induced Liver Injury

open access: yesIraqi Journal of Pharmaceutical Sciences, 2021
The liver is the primary organ for drug metabolism, elimination, Cyclophosphamid is the classical alkylating agent nitrogen mustard, its metabolism into two cytotoxic metabolites, and increase reactive oxygen species that is make liver toxicity. Safranal
Munaf Hashim Zalzala, Victoria S. Kareem
doaj   +1 more source

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