Results 51 to 60 of about 2,506 (151)
Novel Anticancer Capacities of Saffron
Proceedings, 2017 Thanks to poor diagnosis and very limited treatment options, hepatocellular carcinoma (HCC) continues to lead the list of cancer-leading causes of death worldwide. Therefore, alternative therapy is crucial to control HCC.
Amr Amin
doaj +1 more source
Food Science &Nutrition, Volume 14, Issue 5, May 2026.Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200
Amal Elrherabi +8 more
wiley +1 more source
Histopathological and behavioral evaluations of the effects of crocin, safranal and insulin on diabetic peripheral neuropathy in rats [PDF]
Avicenna Journal of Phytomedicine, 2015 Objectives: Crocin and safranal, the major constituents of saffron, exert neuroprotective effects. In the present study, we investigated the effects of crocin and safranal (alone or in combination with insulin) on peripheral neuropathy in diabetic rats.
Amir Farshid, Esmaeal Tamaddonfard
doaj
Biochemistry and Biophysics Reports, 2019 Interaction mechanisms of human serum albumin (HSA) with safranal and crocin were studied using UV–Vis absorption, fluorescence quenching and circular dichroism (CD) spectroscopies as well as molecular docking techniques.
Alaa A. Salem +3 more
doaj +1 more source
Adverse Events of Saffron (Crocus sativus L.): Systematic Review of Current Evidence
Health Science Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background Crocus sativus L., commonly known as saffron, is a widely used spice with a rich history of culinary and medicinal applications. This systematic review aims to compile human data from studies on monopreparations of C. sativus, including stigma powder and other extracts, to evaluate their safety.
Fatemeh Sadat Hasheminasab +3 more
wiley +1 more source
Bioactive volatiles in Sicilian (South Italy) saffron: safranal and its related compounds
, 2017 Sicilian saffron is cultivated mainly in the province of Enna, although cultivation is spreading slowly throughout the region. Volatile constituents which are fundamental for saffron aroma were determined.
CINCOTTA, FABRIZIO +3 more
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Food Science &Nutrition, Volume 14, Issue 4, April 2026.Graphical representation of the metabolic pathways modulated by saffron within defined microbial communities. In the tryptophan pathway, saffron decreased levels of tryptophan and anthranilic acid while increasing concentrations of indole‐3‐acetic acid and tryptamine.
Adelaide E. Horvath +9 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Exercise and dietary polyphenols enhance hippocampal plasticity and cognitive function via complementary molecular mechanisms. Central pathways include BDNF signaling, inflammation control, and mitochondrial regulation. Although synergy is mainly supported by preclinical data, lifestyle‐based strategies show promise for brain health maintenance ...
Zhenyi Zhao, Sima‐sadat Sabihi
wiley +1 more source
Gut Medicine, Volume 2, Issue 1, Page 40-57, March 2026.ABSTRACT Sepsis‐related liver injury (SRLI) involves multiple interrelated pathological processes, including excessive inflammation, oxidative imbalance, mitochondrial dysfunction, dysregulated autophagy, and microcirculatory impairment. Increasing evidence indicates that traditional Chinese medicine (TCM)–based interventions, particularly Chinese ...
Xiang Yunsheng, Yan Yumeng
wiley +1 more source
IN-VITRO ANALYSIS OF POTENTIAL AUTOPHAGY MEDIATED SAFRANAL-SORAFENIB COMBINED EFFECT ON HEPATOCELLULAR CARCINOMA [PDF]
, 2021 Hepatocellular carcinoma (HCC) is one of the most commonly occurring cancers worldwide. The risk factors include obesity, hepatitis, alcoholism, smoking etc. One of the biggest associated challenges is the current treatment strategies.
Farrukh, Aaminah
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