Results 51 to 60 of about 2,346 (204)

Progress on the Protective Effect and the Mechanism of Chinese Medicine Injection and Chinese Medicine Monomeric Small Molecules on Sepsis‐Related Liver Injury

open access: yesGut Medicine, Volume 2, Issue 1, Page 40-57, March 2026.
ABSTRACT Sepsis‐related liver injury (SRLI) involves multiple interrelated pathological processes, including excessive inflammation, oxidative imbalance, mitochondrial dysfunction, dysregulated autophagy, and microcirculatory impairment. Increasing evidence indicates that traditional Chinese medicine (TCM)–based interventions, particularly Chinese ...
Xiang Yunsheng, Yan Yumeng
wiley   +1 more source

Spectroscopic Methods of Edible Flower Authentication and Quality Control for Food Applications

open access: yeseFood, Volume 7, Issue 1, February 2026.
The global demand for edible flowers has increased. Issues such as incorrect species identification, flower product adulteration, contamination, and quality degradation necessitate the application of proper methods for authenticating and controlling the product's quality.
Fidele Benimana   +3 more
wiley   +1 more source

Evaluation of ASC as a therapeutic target for Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract Neuroinflammation is increasingly recognized as a central contributor to the pathogenesis and progression of Alzheimer's disease (AD). The apoptosis‐associated speck‐like protein containing a CARD (ASC), encoded by the PYCARD gene, plays a critical role in the formation of multiple inflammasomes, including NLRP3, a key mediator of inflammation
W. Brent Clayton   +12 more
wiley   +1 more source

Investigating the effect of safranal on Bax and Bcl2 and oxidative stress levels in testis tissue of streptozotocin-induced diabetic rats

open access: yesFiyz̤, 2020
Background: One of the most common endocrine diseases is type 1 diabetes, which causes oxidative stress in testis tissue. Today, in the treatment of diabetes, the tendency toward herbal medicines is increasing day by day.
Ataei Gh, Rahbarian R
doaj  

Novel Anticancer Capacities of Saffron

open access: yesProceedings, 2017
Thanks to poor diagnosis and very limited treatment options, hepatocellular carcinoma (HCC) continues to lead the list of cancer-leading causes of death worldwide. Therefore, alternative therapy is crucial to control HCC.
Amr Amin
doaj   +1 more source

Oral Administration of Crocus sativus Tepals Extract Restores High‐Fat Diet‐Induced Gut Dysbiosis and Modulates Intestinal Inflammation and Hepatic Lipid Metabolism

open access: yesBioFactors, Volume 52, Issue 1, January/February 2026.
This study shows that oral administration of Crocus sativus tepals extract (CTE) restores gut microbiota composition and promotes SCFA‐producing and anti‐inflammatory bacterial genera. It improves intestinal barrier integrity and reduces inflammation in the jejunum and liver, suggesting a possible link between the gut microbiota and the metabolic ...
Biljana Bursać   +9 more
wiley   +1 more source

Safranal and its analogs inhibit Escherichia coli ATP synthase and cell growth

open access: yes, 2017
Safranal, a dominant component of saffron, is known to have antitumor, cytotoxic, and antibacterial properties. In this study, we examined safranal and its structural analogs—thymol, carvacrol, damascenone, cuminol, 2,6,6-trimethyl-2-cyclohexene-1,4 ...
Liu, Mason, Ahmad, Zulfiqar, Amini, Amon
core   +1 more source

Protective Effects of Safranal Against Selenite-Induced Cataract in Rats

open access: yes, 2021
Cataract, which is the opacity inside clear ocular lens of eye, result in the scattering of visible light as it passes via the lens and consequently deterioration in optical image.
Farah A. Mahdi, Munaf H. Zalzala
core   +1 more source

Characterization of human serum albumin's interactions with safranal and crocin using multi-spectroscopic and molecular docking techniques

open access: yesBiochemistry and Biophysics Reports, 2019
Interaction mechanisms of human serum albumin (HSA) with safranal and crocin were studied using UV–Vis absorption, fluorescence quenching and circular dichroism (CD) spectroscopies as well as molecular docking techniques.
Alaa A. Salem   +3 more
doaj   +1 more source

Jeremy Safran: a hero's journey

open access: yesResearch in Psychotherapy: Psychopathology, Process and Outcome, 2019
In this essay I explore Jeremy Safran’s intellectual career as a hero’s journey or monomyth within the specific context of psychotherapy research. I argue that he fits such model in the sense that his work – though deeply informed by theories – was singularly focused and driven by his own sense of his role and mission within the profession. Rather than
openaire   +4 more sources

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