Results 31 to 40 of about 2,506 (151)

Interactions of Apigenin and Safranal with the 5HT1A and 5HT2A Receptors and Behavioral Effects in Depression and Anxiety: A Molecular Docking, Lipid-Mediated Molecular Dynamics, and In Vivo Analysis

Molecules, 2022
Background: The current study utilizes in silico molecular docking/molecular dynamics to evaluate the binding affinity of apigenin and safranal with 5HT1AR/5HT2AR, followed by assessment of in vivo effects of these compounds on depressive and anxious ...
Faiq Amin, Mahmoud A. A. Ibrahim, Syed Rizwan-ul-Hasan, Saima Khaliq, Gamal A. Gabr, Muhammad, Asra Khan, Peter A. Sidhom, Prashant Tikmani, Ahmed M. Shawky, Saara Ahmad, Syed Hani Abidi   +11 more
doaj   +1 more source

The Research of Optimal Conditions for Safranal Extraction From Saffron Flower [PDF]

, 2021
Saffron flower on different stages of its physiological development contains important biologically active compounds (including: protocrocine, picrocrocine, crocine, safranal), which can affect on human organism and it is important to use saffron in food
Khositashvili, M. (M), Aleksandre Chalatashvili, Zaza Baazov, M. Khositashvili, Baazov, Z. (Zaza), Chalatashvili, A. (Aleksandre)   +5 more
core   +2 more sources

The Effect of Safranal on Th1/Th2 Cytokine Balance [PDF]

Iranian Journal of Immunology, 2016
Background: Several biological and medical benefits of Saffron, Crocus sativus (Iridaceae), have been demonstrated. However, mechanisms of actions for purified constituents are greatly unknown.
Reza Feyzi, Mohammad Hossein Boskabady, Seyedeh Masoumeh Seyed hosseini Tamijani, Houshang Rafatpanah, Seyed Abdolrahim Rezaei   +4 more
doaj  

Optimized Isolation of Safranal from Saffron by Solid-Phase Microextraction (SPME) and Rotatable Central Composite Design-Response Surface Methodology (RCCD-RSM)

Separations, 2022
Safranal is the main aroma component of saffron stigmas. It is also a great antioxidant with known pharmacological properties and is a potent indicator for the grading and authentication of saffron.
Panagiota-Kyriaki Revelou, Spyridoula Mouzoula, Marinos Xagoraris, Haralambos Evangelaras, George K. Papadopoulos, Christos S. Pappas, Petros A. Tarantilis   +6 more
doaj   +1 more source

Analgesic Effect of Safranal in Animal Model of Acute Pain; Possible role of the GABAergic Pathway

مجله علمی دانشگاه علوم پزشکی کردستان, 2020
Background and Aim: There are reports for analgesic, anti-inflammatory, hypnotic, neuroprotective and anti-oxidative effects of safranal. The aim of this study was to investigate the analgesic effects of safranal using acute pain method in rat and ...
Esmael Izadpanah, Elham Saei, Omid Abdollahi, Abbas Ahmadi, Mohammad Raman Moloudi   +4 more
doaj  

The comparison of two microextraction methods for the determination of safranal from Iranian saffron

Green Analytical Chemistry, 2022
In this study, safranal as the main component of the pleasant aroma of saffron was extracted and analyzed by two liquid-phase microextraction based methods, namely ultrasound-assisted emulsification microextraction and solidified floating organic drop ...
Mohammad Beiranvand, Alireza Ghiasvand
doaj   +1 more source

Safranal Alleviates Dextran Sulfate Sodium-Induced Colitis and Suppresses Macrophage-Mediated Inflammation

Frontiers in Pharmacology, 2019
Introduction:Crocus sativus (saffron) is widely used in China, Iran, and India for dyeing and as a food additive and medicinal plant. Safranal, as one of the main constituents of saffron, is responsible for its aroma and has been reported to have ...
Peeraphong Lertnimitphun, Yiwen Jiang, Nami Kim, Wenwei Fu, Changwu Zheng, Hongsheng Tan, Hua Zhou, Xue Zhang, Weizhong Pei, Yue Lu, Hongxi Xu, Hongxi Xu   +11 more
doaj   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Safranal Inhibits Angiogenesis via Targeting HIF-1α/VEGF Machinery: In Vitro and Ex Vivo Insights

Frontiers in Oncology, 2022
Nature has a nearly infinite inventory of unexplored phytochemicals and biomolecules that have the potential to treat a variety of diseases. Safranal exhibits anti-cancer property and the present study explores its antiangiogenic property. Hepatocellular
Ali Abdalla, Chandraprabha Murali, Amr Amin, Amr Amin   +3 more
doaj   +1 more source

Saffron aqueous extract effects on paraquat and glyphosate concentration in common carp (Cyprinus carpio) tissues

Agricultural &Environmental Letters, Volume 11, Issue 2, December 2026.
Reduced bioaccumulation of PQ and GLY by saffron extract in Common carp (Cyprinus carpio) tissues Abstract Herbicides such as paraquat (PQ) and glyphosate (GLY) pose ecological and public health risks because of their persistence, bioaccumulation, and toxicity to aquatic organisms. This study evaluated whether aqueous saffron extract (Crocus sativus L.)
Hossein Hammami, Javad Kharkan
wiley   +1 more source