Results 21 to 30 of about 2,506 (151)

Safranal Treatment Improves Hyperglycemia, Hyperlipidemia and Oxidative Stress in Streptozotocin-Induced Diabetic Rats

Journal of Pharmacy & Pharmaceutical Sciences, 2013
Purpose. Clinical research has confirmed the efficacy of several plant extracts in the modulation of oxidative stress associated with diabetes mellitus. Findings indicate that safranal has antioxidant properties.
Saeed Samarghandian, Abasalt Borji, Mohammad Bagher Delkhosh, Fariborz Samini   +3 more
doaj   +2 more sources

Effects of Spirulina Enrichment on Bread Quality: Color, Texture, Volatile, and Sensory Properties. [PDF]

Food Sci Nutr
This study explored how the addition of 1%–2% Spirulina powder affects bread quality, focusing on color, texture, volatile compounds, and sensory characteristics. Spirulina mainly influenced bread color and volatile profile, while texture remained largely unchanged. The enriched samples also showed more pronounced bitter and marine notes.
Masino F, Lo Faro E, Riggio A, Gammaitoni M, Santunione G, Licciardello F, Antonelli A, Montevecchi G.   +7 more
europepmc   +2 more sources

<i>Crocus sativus</i> (Saffron) Aqueous Extract Mediated Green Synthesis of Iron Oxide Nanoparticles and Their In Vitro and In Vivo Biological Investigations. [PDF]

Food Sci Nutr
The Crocus sativus (saffron) aqueous extract mediated green synthesis of iron oxide nanoparticles and their in vitro and in vivo biological investigations. ABSTRACT The present study reports the green synthesis of iron oxide nanoparticles (IONPs) using the aqueous extract of Crocus sativus (saffron) as a natural reducing and stabilizing agent, followed
Rauf A, Shehzad K, Naeem H, Usama S, Ahmad Z, Khan B, Muhammad N, Shafique M, Al-Awthan YS, Bahattab OS, Quradha MM.   +10 more
europepmc   +2 more sources

Safranal Alleviates Cyclophosphamide Induced Testicular Toxicity in Rats. [PDF]

Food Sci Nutr
Safranal, the principal component of Crocus sativus essential oil, is primarily responsible for the characteristic aroma and distinct odor of saffron. Cyclophosphamide (CP), a chemotherapeutic agent commonly used in the treatment of both malignant and ...
Cellat M, Yavaş İ, Uyar A, Etyemez M, Güvenç M.   +4 more
europepmc   +2 more sources

The Therapeutic Effects of <i>Crocus sativus L</i>. and Its Constituents on the Improving Treatment of Azoospermia: A Narrative Review. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Azoospermia, defined as the complete absence of sperm in the ejaculate, is a major cause of male infertility and is classified into obstructive and non‐obstructive forms. While obstructive azoospermia is primarily mechanical in origin, non‐obstructive azoospermia (NOA) is characterized by impaired spermatogenesis and is ...
Khakshour F, Tehran MH, Shahri JJ, Zeynali F, Arab FL.   +4 more
europepmc   +2 more sources

The role of Safranal and saffron stigma extracts in oxidative stress, diseases and photoaging: A systematic review

Heliyon, 2021
Reactive oxygen species (ROS) are produced as a result of various environmental factors and cellular metabolism reactions creating oxidative stress. The reversible oxidative modification on proteins such as cysteine oxidation may be useful and can play ...
Sanju Nanda, Kumud Madan
doaj   +1 more source

Efficacy of safranal to cisplatin-induced nephrotoxicity

, 2017
The aim of the present study was to investigate the effects of safranal on cisplatin-induced nephrotoxicity and oxidative stress in rats. Adult male Sprague–Dawley rats were randomly divided into five groups.
Yasemin Sunucu Karafakıoğlu, Fidan, A. Fatih, Hazman, Omer, Bozkurt, Mehmet Fatih, Mehmet Fatih Bozkurt, Ömer Hazman, A. Fatih Fıdan, Karafakioglu, Yasemin Sunucu   +7 more
core   +2 more sources

Withdrawn: Safranal induces autophagy by AMPK activation and protects neurons against amyloid beta in Alzheimer’s disease

, 2021
This article has been withdrawn by the Editor Purpose: To investigate autophagic induction by safranal and neuroprotection against amyloid beta in Alzheimer’s disease. Methods: Primary neurons and SH-SY5Y cells were used in this study.
Zhu, Manlian, Hua, Ying, Yan, Xiumei, Jiang, Ruilai, Huang, Xiaocheng   +4 more
core   +1 more source

Effect of safranal, a constituent of saffron, on olanzapine (an atypical antipsychotic) induced metabolic disorders in rat [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): Olanzapine, an atypical antipsychotic, causes weight gain and metabolic disorders in humans. Safranal, one of the active components of Crocus sativus (saffron), has been shown to have anti-obesity, lipid and blood pressure lowering and anti-
Sara Malekzadeh, Mahmoud Reza Heidari, Marjan Razavi, Maryam Rameshrad, Hossein Hosseinzadeh   +4 more
doaj   +1 more source

Safrana l Prevents Prostate Cancer Recurrence by Blocking the Re-activation of Quiescent Cancer Cells via Downregulation of S-Phase Kinase-Associated Protein 2

Frontiers in Cell and Developmental Biology, 2020
The re-proliferation of quiescent cancer cells is considered to be the primary contributor to prostate cancer (Pca) recurrence and progression. In this study, we investigated the inhibitory effect of safranal, a monoterpene aldehyde isolated from Crocus ...
Xue Jiang, Yang Li, Ji-ling Feng, Ji-ling Feng, Wan Najbah Nik Nabil, Wan Najbah Nik Nabil, Rong Wu, Yue Lu, Hua Liu, Zhi-chao Xi, Hong-xi Xu, Hong-xi Xu   +11 more
doaj   +1 more source