Results 91 to 100 of about 5,332 (163)

Protective effect of crocin on liver toxicity induced by morphine

, 2016
Crocin, a bioactive molecule of saffron can be purely isolated from the saffron extract. It has different pharmacological effects such as antioxidant and anticancer activities. Morphine is an opioid analgesic drug.
Mohammad Reza Salahshoor, Cyrus Jalili, Seyran Kakabaraei, Shiva Roshankhah, Mojtaba khashiadeh   +4 more
core  

Comparative Evaluation of Antidepressant and Anxiolytic Effects of Escitalopram, Crocin, and their Combination in Rats

Advanced Biomedical Research
Background: Chronic stress can lead to anxiety and depression. Escitalopram is a selective serotonin reuptake inhibitor (SSRI), and crocin is a natural compound derived from saffron.
Mehran Joodaki, Maryam Radahmadi, Hojjatallah Alaei   +2 more
doaj   +1 more source

Crocin production and its prospect as biocolorant in polymer products

, 2021
The essential carotenoids for humans are found in plants with red, orange or yellow pigmentation. These carotenoids are generally lipophilic, however, some of the plants produce very unique hydrophilic carotenoid compounds.
Othman, Rashidi, Ramya, Razanah, Mohd Latif, Nur Hanie, Wan Sulaiman, Wan Syibrah Hanisah, Mohd Hatta, Farah Ayuni   +4 more
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Crocin as a novel therapeutic agent against colitis

, 2019
Ulcerative colitis is a chronic inflammatory bowel disease with high incidence and prevalence worldwide. To investigate the therapeutic potency of crocin, as a pharmacologically active component of saffron, in dextran sodium sulfate (DSS)-induced colitis
Khazaei, M., Bahreyni, A., Hashemzehi, M., Behnam-Rassouli, R., Shafiee, M., Ariakia, F., Rahmani, F., Ryzhikov, M., Hassanian, S.M., Rezaei, N., Moradi Marjaneh, R., Avan, A., Pashirzad, M.   +12 more
core  

Protective effect of crocin on gentamicin-induced nephrotoxicity in rats [PDF]

, 2016
Objective(s): Gentamicin is used for the treatment of Gram-negative bacterial infections. However, gentamicin administration is limited because of nephrotoxicity.
Houshang Najafi, Seyed Hamid Madani, Zeynab Mohamadi Yarijani   +2 more
core   +1 more source

Oral administration of crocin significantly alleviated anxiety, and depressive-like behavior following ethanol and nicotine abstinence in adolescent male rats

Scientific Reports
There are increasing concerns about nicotine (Nic) and ethanol (Eth) dependence and more importantly the detrimental effects of Nic abstinence among adolescents.
Samaneh Kakhki, Elham Fadavi Razdabi, Faezeh Mohammadzadeh, Ali Abbaszade-Cheragheali, Mahshid Jomehpour, Farimah Beheshti   +5 more
doaj   +1 more source

Cardiotoxicological assessment of crocin-coated silver nanoparticles in an experimental rat model. [PDF]

Toxicol Rep
Ziaaldini MAA, Fakhrtaha T, Samarghandian S, Farkhondeh T.   +3 more
europepmc   +1 more source

Crocin I delays cellular senescence potentially via modulating SIRT1/PKM2 expression to improve lactate homeostasis <i>in vitro</i>. [PDF]

Exp Ther Med
Fu Y, Ding Z, Chang Y, Wu C, Wang S, Mao G, Su H.   +6 more
europepmc   +1 more source

Correction: Crocin promotes ferroptosis in gastric cancer via the Nrf2/GGTLC2 pathway. [PDF]

Front Pharmacol
Yan N, Li G, Zhao L, Guo Q, Yang J, Liu J, Zhou W, Gao Y, Luo Y.   +8 more
europepmc   +1 more source

Effects of crocin on anxiety, depression, and hippocampal BDNF expression in streptozotocin-induced diabetic rats. [PDF]

Ann Med Surg (Lond)
Rahimi K, Afandak SR, Razavi F, Segoli A, Maharlooei FS.   +4 more
europepmc   +1 more source