Results 91 to 100 of about 9,307,341 (282)

Improvement with Infliximab of a Disseminated Sarcoidosis in a Patient with Crohn’s Disease

open access: yesCase Reports in Pulmonology, 2014
Sarcoidosis and Crohn’s disease are systemic granulomatous disorders affecting the lung and the intestine, respectively, with variable involvement of other organs and are seldom associated.
Nader Chebib   +4 more
doaj   +1 more source

A Rare Manifestation of Crohn's Disease: Sinonasal Granulomatosis. Report of a Case and Review of Literature

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2014
Crohn’s disease is a granulomatous inflammatory bowel disease. Its pathologic findings include non-contiguous chronic inflammation and non-caseating granulomas, sometimes with extra-intestinal localizations.
Lilia Baili   +6 more
doaj   +1 more source

Crohn’s Disease: a Role of Gut Microbiota and Nod2 Gene Polymorphisms in Disease Pathogenesis

open access: yesActa Medica, 2014
Crohn’s disease is a chronic immune-mediated intestinal inflammation targeted against a yet incompletely defined subset of commensal gut microbiota and occurs on the background of a genetic predisposition under the influence of environmental factors ...
Lucia Hrnčířová   +3 more
doaj   +1 more source

Molecular bases and role of viruses in the human microbiome. [PDF]

open access: yes, 2014
Viruses are dependent biological entities that interact with the genetic material of most cells on the planet, including the trillions within the human microbiome.
Abeles, Shira R, Pride, David T
core   +1 more source

Doença de Crohn vulvoperineal responsiva ao metronidazole [PDF]

open access: yes, 2013
Crohn's disease is a multisystem chronic granulomatous inflammatory disease that primarily affects the gastrointestinal tract. In the majority of the cases, the cutaneous manifestations follow the intestinal disease, but occasionally dermatological ...
Alves, R.   +4 more
core   +1 more source

Azathioprine-Induced Peripheral T Cell Apoptosis And Drug Response In Patients With Crohn’s Disease [PDF]

open access: yes, 2011
Background and Aim: the long time interval for a trial of thioupurine therapy and the potential side effects in spite of the proven efficacy, do not encourage their use as early therapeutic option in Crohn’s Disease (CD).
Cossu, Andrea
core  

A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells. [PDF]

open access: yes, 2019
Microbial metabolites are an emerging class of mediators influencing CD4+ T-cell function. To advance the understanding of direct causal microbial factors contributing to Crohn's disease, we screened 139 predicted Crohn's disease-associated microbial ...
Borneman, James   +19 more
core   +1 more source

Fistulizing Crohn's Disease

open access: yesClinical and Translational Gastroenterology, 2017
Fistulas still represent one of the most important complications in patients with Crohn's disease (CD). At least one third of CD patients suffer from fistulas during their disease course and amongst them longstanding remission of complex fistulas occurs only in about one third. So far, fistula pathogenesis is only partially understood.
Scharl, Michael   +2 more
openaire   +3 more sources

The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors [PDF]

open access: yes, 2015
OBJECTIVE: Gut barrier is a functional unit organized as a multi-layer system and its multiple functions are crucial for maintaining gut homeostasis. Numerous scientific evidences showed a significant association between gut barrier leaking and gastro ...
Bruno, G   +5 more
core  

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