Improvement with Infliximab of a Disseminated Sarcoidosis in a Patient with Crohn’s Disease
Sarcoidosis and Crohn’s disease are systemic granulomatous disorders affecting the lung and the intestine, respectively, with variable involvement of other organs and are seldom associated.
Nader Chebib +4 more
doaj +1 more source
Crohn’s disease is a granulomatous inflammatory bowel disease. Its pathologic findings include non-contiguous chronic inflammation and non-caseating granulomas, sometimes with extra-intestinal localizations.
Lilia Baili +6 more
doaj +1 more source
Crohn’s Disease: a Role of Gut Microbiota and Nod2 Gene Polymorphisms in Disease Pathogenesis
Crohn’s disease is a chronic immune-mediated intestinal inflammation targeted against a yet incompletely defined subset of commensal gut microbiota and occurs on the background of a genetic predisposition under the influence of environmental factors ...
Lucia Hrnčířová +3 more
doaj +1 more source
Molecular bases and role of viruses in the human microbiome. [PDF]
Viruses are dependent biological entities that interact with the genetic material of most cells on the planet, including the trillions within the human microbiome.
Abeles, Shira R, Pride, David T
core +1 more source
Doença de Crohn vulvoperineal responsiva ao metronidazole [PDF]
Crohn's disease is a multisystem chronic granulomatous inflammatory disease that primarily affects the gastrointestinal tract. In the majority of the cases, the cutaneous manifestations follow the intestinal disease, but occasionally dermatological ...
Alves, R. +4 more
core +1 more source
Azathioprine-Induced Peripheral T Cell Apoptosis And Drug Response In Patients With Crohn’s Disease [PDF]
Background and Aim: the long time interval for a trial of thioupurine therapy and the potential side effects in spite of the proven efficacy, do not encourage their use as early therapeutic option in Crohn’s Disease (CD).
Cossu, Andrea
core
A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells. [PDF]
Microbial metabolites are an emerging class of mediators influencing CD4+ T-cell function. To advance the understanding of direct causal microbial factors contributing to Crohn's disease, we screened 139 predicted Crohn's disease-associated microbial ...
Borneman, James +19 more
core +1 more source
Endometrial Stricture of Small Intestine Simulating Crohn's Disease [PDF]
H. C. Thompson
openalex +1 more source
Fistulas still represent one of the most important complications in patients with Crohn's disease (CD). At least one third of CD patients suffer from fistulas during their disease course and amongst them longstanding remission of complex fistulas occurs only in about one third. So far, fistula pathogenesis is only partially understood.
Scharl, Michael +2 more
openaire +3 more sources
The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors [PDF]
OBJECTIVE: Gut barrier is a functional unit organized as a multi-layer system and its multiple functions are crucial for maintaining gut homeostasis. Numerous scientific evidences showed a significant association between gut barrier leaking and gastro ...
Bruno, G +5 more
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