Results 71 to 80 of about 4,909,303 (275)

Meckel's Diverticulum in Crohn's Disease

Canadian Journal of Gastroenterology, 2001
Meckel's diverticulum is a congenital abnormality of the distal ileum associated with failed vitelline duct closure. Detailed pathological studies have estimated its frequency to be about 2% of the general population, and it has been anecdotally recorded
Hugh J Freeman
doaj   +1 more source

Necrobiosis lipoidica of the breast associated with Crohn’s disease: a case report

Journal of Medical Case Reports, 2023
Background Necrobiosis lipoidica located to the breast; without evidence of glucose intolerance, is extremely rare, and its association to Crohn’s disease is not usual.
Awatef Kelati, François Durupt, Brigitte Balme   +2 more
doaj   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

Advanced Science, EarlyView.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun, Teng Ma, Hao Jin, Zelong Li, Yi Cheng, Jingjin Li, Lai‐Yu Kwok, Zhihong Sun   +7 more
wiley   +1 more source

Uhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease

Advanced Science, EarlyView.
Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang, Xin‐Rong Xu, Hui‐Lin Zhang, Qi‐Meng Zhu, Xin‐Yuan Li, Xi‐Peng Shang, Jing‐Hui Du, Christophe Morisseau, Feng Qiu, Cheng‐Peng Sun   +9 more
wiley   +1 more source

Metastatic Crohn′s disease

Indian Journal of Medical Research, 2015
A 51 year old man presented to the department of Dermatology, Regional University Hospital of Málaga, Málaga, Spain, in May 2013, with remarkable lesions on the perineal, perianal and gluteal regions reaching the top of the lower limbs, which he had first noted two years earlier.
Pérez-Belmonte, Luis-Miguel, Gómez-Moyano, Elisabeth   +1 more
openaire   +3 more sources

ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment [PDF]

, 2019
This article is the second in a series of two publications relating to the European Crohn's and Colitis Organisation [ECCO] evidence-based consensus on the management of Crohn's disease.
Kucharzik, Torsten, Sabino, Joao, Bager, Palle, Adamina, Michel,, Verstockt, Bram, El-Hussuna, Alaa, Juillerat, Pascal,, Adamina, Michel, Biancone, Livid, Gingert, Christian, European Crohn’s and Colitis Organisation [ECCO], Frei-Lanter, Cornelia,, Torres, Joana, Biancone, Livia, Zmoraas, Oded, Vavricka, Stephan,, Katsanos, Konstantinos,, Lorenzo, Marien González, Raine, Tim,, Magro, Fernando, Kopylov, Uri, Rosa, Isadora, Burisch, Johan, Doherty, Glen, Kopylov, Uri,, Spinelli, Antonino, Warusavitarne, Janindra,, El-Hussuna, Alaa,, Kucharzik, Torsten,, Sabino, Joao,, Uzzan, Mathieu,, Gomollon, Fernando, Marshall, John Kenneth,, Savarino, Edoardo, Furfaro, Federica, Burisch, Johan,, Raine, Tim, Pellino, Gianluca,, Fiorino, Gionata, Gordon, Hannah, Hlavaty, Tibor, Gionchetti, Paolo,, Maaser, Christian,, Frei-Lanter, Cornelia, Gisbert, Javier P.,, Myrelid, Pär,, Furfaro, Federica,, Zmora, Oded,, Torres, Joana,, Krustins, Eduards, Gisbert, Javier P, Verstockt, Bram,, Maaser, Christian, Vavricka, Stephan, Krustins, Eduards,, Bokemeyer, Bernd,, Uzzan, Mathieu, Ellul, Pierre,, Myrelid, Pär, Armuzzi, Alessandro,, Bachmann, Oliver, Stassen, Laurents, Gingert, Christian,, Stassen, Laurents,, Juillerat, Pascal, Bokemeyer, Bernd, Bager, Palle,, Collins, Paul,, Doherty, Glen,, Armuzzi, Alessandro, Bachmann, Oliver,, Katsanos, Konstantinos, Lytras, Theodore,, Spinelli, Antonino,, Pellino, Gianluca, Ellul, Pierre, González Lorenzo, Marien, Bossuyt, Peter,, Bonovas, Stefanos, Marshall, John Kenneth, Gomollon, Fernando,, Collins, Paul, Gionchetti, Paolo, Rosa, Isadora,, Warusavitarne, Janindra, Bossuyt, Peter, Fiorino, Gionata,, Bonovas, Stefanos,, Gordon, Hannah,, Gisbert, Javier P., Lorenzo, Marien Gonzalez,, Biancone, Livia,, Hlavaty, Tibor,, Lytras, Theodore, Savarino, Edoardo,, Zmora, Oded, Magro, Fernando,   +96 more
core   +3 more sources

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

Pharmacotherapy of Crohn's disease

, 2015
Overview of the pathophysiology of Crohn's disease. The symptomatic and direct pharmacotherapy of the disease. Further studies and research trials connected to pharmacotherapy of Crohn'sáltalános orvosangolegységes ...
Olafsson, Steinar
core  

OC-163 identification of inflammatory bowel disease (IBD) using field asymmetric ion mobility spectrometry (FAIMS) [PDF]

, 2012
Introduction Resident colonic bacteria, principally anaerobes and firmicutes, ferment undigested fibre. The resultant volatile organic compounds (VOCs) formed are dissolved in the faeces but also absorbed and excreted in the urine.
Thomas, M. G., Hetherington, E., Arasaradnam, Ramesh P., Ouaret, N., Covington, James A., Quraishi, M. N., Nwokolo, Chuka U., Bardhan, Karna Dev   +7 more
core   +1 more source