Results 91 to 100 of about 10,538,494 (333)
Journal of Medical Case Reports, 2011 Introduction Crohn's disease is a chronic inflammatory bowel disease of unknown etiology which may affect any part of the bowel. Fistulas are a common and often serious complication of Crohn's disease. The treatment for fistulizing Crohn's disease can be
Simopoulos Konstantinos +7 more
doaj +1 more source
A Rare Presentation of Crohn's Disease
, 2008 Free peritoneal perforation is a rare complication of Crohn's disease with a report of only 100 cases in the literature. It needs an emergency exploration and an unaware general surgeon is confounded in intraoperative decision-making.
Bhat, Sriram M +10 more
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Multifocal posterior uveitis in Crohn's disease [PDF]
, 2007 PURPOSE To report a case of rare posterior eye manifestation of Crohn's disease preceding recurrence of inflammatory bowel disease. METHODS Case report with ophthalmoscopic findings, fluorescein/indocyanin green angiograms, automated perimetry and ...
Dohrmann, Jürgen +3 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) +
Jose U. Scher +12 more
wiley +1 more source
The safety of vedolizumab for ulcerative colitis and Crohn's disease
Gut, 2016 Objective Vedolizumab is a gut-selective antibody to α4β7 integrin for the treatment of ulcerative colitis (UC) and Crohn's disease (CD). We report an integrated summary of the safety of vedolizumab.
J. Colombel +13 more
semanticscholar +1 more source
The role of the NOD2 gene in the pathogenesis of Crohn’s disease
, 2009 Introduction: Crohn’s disease is characterised by an abnormal inflammatory response possibly induced by components of enteric bacteria, in genetically susceptible individuals.
Chalmers-Watson, T.A.
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ABO histo-blood group might modulate predisposition to Crohn's disease and affect disease behavior [PDF]
, 2014 BACKGROUND AND AIMS: ABO encodes a glycosyltranferase which determines the major human histo-blood group. The FUT2 fucosyltransferase allows expression of ABO antigens on the gastrointestinal mucosa and in bodily secretions (secretor phenotype).
A. Cassinotti +14 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim There is an unmet need for more effective therapies in inflammatory bowel disease (IBD). A single drug that blocks multiple distinct pathogenic pathways may offer therapeutic benefit superior to current monotherapies. PF‐07261271, a bispecific antibody targeting both the p40 subunit of interleukin‐12/23 and tumour necrosis factor‐like cytokine 1A ...
Srividya Neelakantan +11 more
wiley +1 more source
Smoking in inflammatory bowel diseases: Good, bad or ugly?
, 2007 Smoking is an important environmental factor in inflammatory bowel disease (IBD), having different effects in ulcerative colitis (UC) and Crohn’s disease (CD).
Peter Laszlo Lakatos +5 more
core +1 more source