Results 121 to 130 of about 9,113,589 (351)

Multiple Enteroenteric Fistulas- Crohn’s Disease- A Case Report

open access: yesIranian Journal of Public Health, 2015
Crohn's disease is a type of chronic inflammatory bowel disease (IBD) of unknown etiology that may affect any part of the gastrointestinal tract from mouth to anus and shows extra-intestinal involvement. It characteristically shows skip lesions.
Hasnain Abbas DHARAMSHI   +8 more
doaj  

A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn's disease patients.

open access: yesPLoS ONE, 2018
BackgroundThe chronic remitting and relapsing intestinal inflammation characteristic of Crohn's disease frequently leads to fibrosis and subsequent stenosis of the inflamed region.
Andrew Y F Li Yim   +11 more
doaj   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

open access: yesIbrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen   +10 more
wiley   +1 more source

Integrin β6 expression in colorectal cancer cells promotes liver metastasis through enhanced adhesion to endothelial fibronectin

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Integrins are critical mediators of cell adhesion and migration and have been implicated in cancer progression. Here, the authors show that endothelial cells in target organs of colorectal cancer metastasis express fibronectin, and that colorectal cancer tumour cells can bind fibronectin through integrin β6. This interaction is resistant to
Chiara Van Passen   +16 more
wiley   +1 more source

Fragility Index analysis for robustness of evidence in Randomized Controlled Trials in National Comprehensive Cancer Network (NCCN) guidelines for rectal cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Data from randomized controlled trials (RCTs) forms a foundation for rectal cancer treatment guidelines. The reliability of such data is therefore essential for evidence‐based clinical decision‐making. This study assessed the robustness of RCTs cited in the latest National Comprehensive Cancer Network (NCCN) guidelines for rectal cancer ...
Nir Horesh   +8 more
wiley   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng   +4 more
wiley   +1 more source

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