Results 81 to 90 of about 89,895 (292)

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Duodenal Crohn’s Disease [PDF]

open access: yesInflammatory Bowel Diseases, 2018
Symptomatic duodenal Crohn's disease (CD) is an uncommon disease presentation, especially in isolation. The most common duodenal disease phenotype is stricturing disease rather than inflammatory or perforating. Most patients are asymptomatic and are therefore diagnosed incidentally by cross-sectional imaging or endoscopy.
openaire   +2 more sources

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

open access: yesIbrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen   +10 more
wiley   +1 more source

A Rare Manifestation of Crohn's Disease: Sinonasal Granulomatosis. Report of a Case and Review of Literature

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2014
Crohn’s disease is a granulomatous inflammatory bowel disease. Its pathologic findings include non-contiguous chronic inflammation and non-caseating granulomas, sometimes with extra-intestinal localizations.
Lilia Baili   +6 more
doaj   +1 more source

Organ‐sparing strategies in patients with MSI/dMMR tumors including Lynch syndrome: Current state of the art and future perspectives for clinical decision‐making

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Deficiency in DNA mismatch repair (dMMR) is a common pathway of carcinogenesis across different tumor types and confers a characteristic microsatellite instability‐high (MSI‐H) molecular phenotype. The MSI‐H/dMMR phenotype may arise from an inherited pathogenic variant in the context of Lynch syndrome and is most frequently observed in ...
Martin Duval   +8 more
wiley   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng   +4 more
wiley   +1 more source

Anorectal Crohn's disease

open access: yesJournal of British Surgery, 1979
Summary Four hundred and twenty-three patients with Crohn's disease have been reviewed, 48 of whom had isolated anorectal involvement—an incidence of 11·4 per cent. These patients were compared with 48 randomly selected and sex-matched cases who presented with isolated ileocolic disease.
N S, Williams, J, Macfie, L R, Celestin
openaire   +2 more sources

Long‐term results of the Musset surgical technique in the treatment of recto‐vaginal fistulas

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Recto‐vaginal fistulas (RVF) are a rare pathology, mostly affecting developing countries. They are mainly obstetrical (88% of cases) and have an incidence of 0.5%. Musset's surgical technique in the management of RVF has been the subject of few studies and there is little data in the literature concerning the evaluation of its long ...
Joy Bloomfield   +5 more
wiley   +1 more source

P029 Inflammasome activation P2X7-dependent in Crohn's disease [PDF]

open access: bronze, 2013
A. Zelante   +7 more
openalex   +1 more source

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