Results 181 to 190 of about 97,874 (310)

Population Pharmacokinetics and Exposure–Response Relationships of Etrolizumab in Patients with Moderately‐to‐Severely Active Crohn's Disease

The Journal of Clinical Pharmacology, EarlyView.
Abstract This study aimed to characterize the pharmacokinetics (PK) of etrolizumab, an IgG1‐humanized monoclonal anti‐β7 integrin antibody, and assess its exposure–response (ER) relationship for key clinical outcomes in patients with moderately‐to‐severely active Crohn's disease.
Anita Moein, Jakob Ribbing, Moustafa M. A. Ibrahim, Wenhui Zhang, Nastya Kassir   +4 more
wiley   +1 more source

Prevalence Rates and an Evaluation of Reported Risk Factors for Osteonecrosis (Avascular Necrosis) in Crohn’s Disease [PDF]

, 2000
Hugh James Freeman, Katy J Freeman
openalex   +1 more source

Additional file 1: of Prognostic biomarkers to identify patients destined to develop severe Crohnâ s disease who may benefit from early biological therapy: protocol for a systematic review, meta-analysis and external validation

, 2016
Crohnâ s systematic review definitions and analysis. (DOC 99 kb)
Halligan, Steve, Boone, Darren, Gauraang Bhatnagar, Ahmad, Tariq, Bloom, Stuart, Rodriguez-Justo, Manuel, Taylor, Stuart, Mallett, Susan   +7 more
openaire   +1 more source

STAT3 Genotypic Variant rs744166 and Increased Tyrosine Phosphorylation of STAT3 in IL-23 Responsive Innate Lymphoid Cells during Pathogenesis of Crohn\u27s Disease [PDF]

, 2019
Crohn\u27s disease (CD) results from dysregulated immune responses to gut microbiota in genetically susceptible individuals, affecting multiple areas of the gastrointestinal tract.
Glover, Sarah C., Iqbal, Atif, Li, Jian, Tan, Sanda A., Tang, Ying   +4 more
core   +1 more source

Therapeutic Use of Cannabis Derivatives and Their Analogs for Autism Spectrum Disorder: A Systematic Review

The Journal of Clinical Pharmacology, EarlyView.
Abstract Autism spectrum disorders are characterized by some difficulties with social interactions and communication, atypical patterns of behavior, and unusual reactions to emotions. Studies have found promising results regarding the effects of cannabis on autism.
Rachel Riera, Isabela Porto de Toledo, Cecília Menezes Farinasso, Rafael Leite Pacheco, Roberta Borges Silva, Verônica Colpani, Ana Luiza Cabrera Martimbianco, Camila Monteiro Cruz, Patrícia do Carmo Silva Parreira, Carolina de Oliveira Cruz Latorraca   +9 more
wiley   +1 more source

Crohn’s disease in Wales, 1967–1976; an epidemiological survey based on hospital admissions

, 1980
J F Mayberry, J. Rhodes, R G Newcombe
openalex   +1 more source

Shorter Disease Duration Is Associated With Higher Rates of Response to Vedolizumab in Patients With Crohn's Disease But Not Ulcerative Colitis. [PDF]

, 2019
Background & aimsPatients with Crohn's disease (CD), but not ulcerative colitis (UC), of shorter duration have higher rates of response to tumor necrosis factor (TNF) antagonists than patients with longer disease duration.
Aniwan, Satimai, Bohm, Matthew, Boland, Brigid S, Chablaney, Shreya, Chang, Shannon, Colombel, Jean-Frederic, Dulai, Parambir S, Faleck, David M, Fischer, Monika, Gupta, Nitin, Hirten, Robert, Hudesman, David, Kane, Sunanda, Kesar, Varun, Kochhar, Gursimran, Koliani-Pace, Jenna L, Lasch, Karen, Loftus, Edward V, Lukin, Dana, Luo, Michelle, Meserve, Joseph, Sandborn, William J, Sands, Bruce E, Shashi, Preeti, Shen, Bo, Shmidt, Eugenia, Siegel, Corey A, Singh, Siddharth, Sultan, Keith, Swaminath, Arun, Ungaro, Ryan, Varma, Sashidhar, Weiss, Aaron, Winters, Adam   +33 more
core  

Effect of smoking over one pack daily on implant healing and health: A cohort study

Journal of Periodontology, EarlyView.
Abstract Background This prospective cohort trial examines the effects of heavy smoking on peri‐implant marginal bone loss (MBL) and implant survival rates over 15 months. Methods Thirty subjects, categorized as either smokers (more than 20 cigarettes daily for over 5 years) or non‐smokers, were initially recruited with pocket depths ≤ 5 mm and at ...
Yaniv Mayer, Eran Gabay, Eli E. Machtei, Eli Regev, Ofir Ginesin, Zvi Gutmacher, Jacob Horwitz, Luigi Canullo, Jamil Awad Shibli, Hadar Giladi Zigdon   +9 more
wiley   +1 more source

State‐of‐the‐art review of blenderized diets—Status and future directions

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract This state‐of‐the‐art review was produced by a multidisciplinary team composed of pediatric gastroenterology and nutrition healthcare providers to provide a comprehensive overview of the use of blenderized tube feeds (BTFs). The team developed 12 vital questions to address gaps in the current understanding and practice of using BTFs, then ...
Sharon Weston, Anushree Algotar, Sara Karjoo, Megan Gabel, Patrice Kruszewski, Debora Duro, Senthilkumar Sankararaman, Danielle Wendel, Shweta S. Namjoshi, Ruba A. Abdelhadi, David Kawatu, Mark R. Corkins, Timothy Sentongo   +12 more
wiley   +1 more source

Mucosal healing and a fall in mucosal pro‐inflammatory cytokine mRNA induced by a specific oral polymeric diet in paediatric Crohn’s disease [PDF]

, 2000
Fell, Paintin, Arnaud‐Battandier, R. Mark Beattie, Hollis, Kitching, Donnet‐Hughes, MacDonald, Walker‐Smith   +8 more
openalex   +1 more source