Sweet's syndrome in a patient with Crohn's disease: a case report
Background Sweet's syndrome, also known as acute febrile neutrophilic dermatosis, has been associated with malignancy, autoimmune disease and collagen vascular disease. The association of Crohn's disease and Sweet's syndrome is rare.
Mustafa Nadia M, Lavizzo Mark
doaj +1 more source
BowSaw: inferring higher-order trait interactions associated with complex biological phenotypes [PDF]
Machine learning is helping the interpretation of biological complexity by enabling the inference and classification of cellular, organismal and ecological phenotypes based on large datasets, e.g. from genomic, transcriptomic and metagenomic analyses.
Dimucci, Demetrius +2 more
core +2 more sources
A series of clinical practice guidelines were recently developed by the Canadian Association of Gastroenterology (CAG) to provide clinicians with recommendations for the medical management of nonhospitalized ulcerative colitis (UC) patients.
A Hillary Steinhart, Aida Fernandes
doaj +1 more source
Efficacy of adalimumab as second-line therapy in a pediatric cohort of crohn’s disease patients who failed infliximab therapy: The Italian society of pediatric gastroenterology, hepatology, and nutrition experience [PDF]
Background: Adalimumab (Ada) treatment is an available option for pediatric Crohn’s disease (CD) and the published experience as rescue therapy is limited.
Accomando S. +15 more
core +1 more source
Context and Objectives Focally enhanced gastritis and macrophage microaggregates are found in the upper gastrointestinal involvement of Crohn’s disease, and may reflect an underlying defective innate immunity.
Marcia Henriques de MAGALHÃES-COSTA +5 more
doaj +1 more source
The role of the novel Th17 cytokine IL-26 in intestinal inflammation [PDF]
Background and aims: Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in human disease is completely unknown. The aim of this study was to analyse its
Auernhammer, Christoph J. +7 more
core +1 more source
PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites. [PDF]
Genome-wide association studies identified a PTGER4 expression-modulating region on chromosome 5p13.1 as Crohn's disease (CD) susceptibility region. The study aim was to test this association in a large cohort of patients with inflammatory bowel disease (
Achkar, Jean-Paul +14 more
core +9 more sources
Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli. [PDF]
Pathobiont expansion, such as that of adherent-invasive Escherichia coli (AIEC), is an emerging factor associated with inflammatory bowel disease. The intestinal epithelial barrier is the first line of defense against these pathogens.
McCole, Declan F, Shawki, Ali
core +1 more source
Safety aspects of infliximab in inflammatory bowel disease patients - A retrospective cohort study in 100 patients of a German University Hospital [PDF]
Background: Infliximab, a chimeric anti-tumour necrosis factor monoclonal antibody with potent anti-inflammatory effects, represents an effective treatment option in patients with severe inflammatory bowel disease (IBD).
Ali Y +11 more
core +1 more source
The Prevalence of Headache in Crohn’s Disease: Single-Center Experience
Objectives. This study is aimed at studying the prevalence and characteristics of different types of headaches in patients with Crohn’s disease. Materials and Methods.
Ulker Anadol Kelleci +6 more
doaj +1 more source

