Results 41 to 50 of about 102,860 (309)

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Additional file 2: of Identifying Crohnâ s disease signal from variome analysis

, 2019
Supplementary methods and results. (PDF 4720 kb)
Yanran Wang, Miller, Maximilian, Astrakhan, Yuri, Britt-Sabina Petersen, Schreiber, Stefan, Franke, Andre, Bromberg, Yana   +6 more
openaire   +1 more source

PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background. [PDF]

, 2012
Genome-wide association studies identified PTPN2 (protein tyrosine phosphatase, non-receptor type 2) as susceptibility gene for inflammatory bowel diseases (IBD).
Darina Czamara, Seiderer, J., Ochsenkühn, Thomas, Nazanin Karbalai (177982), Beigel, F., Julia Seiderer (107820), Wagner, Johanna, Glas, J., Cornelia Tillack (174718), Friedrich, Matthias, Christian Steib (174731), Czamara, D., Jürgen Glas (107816), Tillack, Cornelia, Nazanin Karbalai, Stallhofer, Johannes, Torsten Olszak (107835), Brand, Stephan, Karbalai, N., Göke, B., Florian Beigel (174724), Thomas Ochsenkühn, Beigel, Florian, Matthias Friedrich (174721), Thomas Ochsenkühn (174734), Stallhofer, J., Ochsenkühn, T., Johannes Stallhofer, Matthias Friedrich, Wetzke, M., Darina Czamara (107824), Stephan Brand (107861), Cornelia Tillack, Julia Diegelmann, Steib, Christian, Göke, Burkhard, Wagner, J., Friedrich, M., Seiderer, Julia, Glas, Jürgen, Diegelmann, J., Burkhard Göke (109829), Martin Wetzke, Burkhard Göke, Christian Steib, Stephan Brand, Brand, S., Steib, C., Czamara, Darina, Martin Wetzke (107833), Julia Diegelmann (107830), Jürgen Glas, Johanna Wagner (174709), Johanna Wagner, Wetzke, Martin, Karbalai, Nazanin, Diegelmann, Julia, Johannes Stallhofer (174728), Torsten Olszak, Olszak, T., Florian Beigel, Julia Seiderer, Olszak, Torsten, Tillack, C.   +63 more
core   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Two for One: Coexisting Ulcerative Colitis and Crohn’s Disease

Canadian Journal of Gastroenterology, 2002
Three cases of coexisting ulcerative colitis and Crohn’s disease are presented. In the first case, the patient had a long-standing history of ulcerative proctitis before developing Crohn’s colitis.
Grant I Chen, Fred Saibil, Izabella Morava-Protzner   +2 more
doaj   +1 more source

Additional file 11: of Genome analysis of E. coli isolated from Crohnâ s disease patients

, 2017
Bacteriocin production test in CD-associated strains. (DOC 42Â kb)
Rakitina, Daria, Manolov, Alexander, Kanygina, Alexandra, Garushyants, Sofya, Baikova, Julia, Alexeev, Dmitry, Ladygina, Valentina, Kostryukova, Elena, Larin, Andrei, Semashko, Tatiana, Karpova, Irina, Babenko, Vladislav, Ismagilova, Ruzilya, Malanin, Sergei, Gelfand, Mikhail, Ilina, Elena, Gorodnichev, Roman, Lisitsyna, Eugenia, Aleshkin, Gennady, Scherbakov, Petr, Khalif, Igor, Shapina, Marina, Maev, Igor, Andreev, Dmitry, Govorun, Vadim   +24 more
openaire   +1 more source

CEACAM6 gene variants in inflammatory bowel disease. [PDF]

, 2011
The carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) acts as a receptor for adherent-invasive E. coli (AIEC) and its ileal expression is increased in patients with Crohn's disease (CD). Given its contribution to the pathogenesis of CD,
Seiderer, J., Darina Czamara, Seiderer Julia, Ochsenkühn, Thomas, Ulrich Lass, Fries, C., Beigel, F., Glas, J., Müller-Myhsok, B., Czamara, D., Bertram Müller-Myhsok, Diegelmann Julia, Fries Christoph, Tillack, Cornelia, Lass, U., Pfennig Simone, Brand, Stephan, Göke, B., Brand Stephan, Thomas Ochsenkühn, Weidinger Maria, Olszak Torsten, Beigel, Florian, Weidinger, Maria, Ochsenkühn, T., Christiane Wolf, Wolf, Christiane, Cornelia Tillack, Julia Diegelmann, Beigel Florian, Müller-Myhsok Bertram, Göke, Burkhard, Lass Ulrich, Fries, Christoph, Pfennig, S., Pfennig, Simone, Peter Lohse, Seiderer, Julia, Glas, Jürgen, Diegelmann, J., Lohse, P., Christoph Fries, Ochsenkühn Thomas, Müller-Myhsok, Bertram, Weidinger, M., Burkhard Göke, Göke Burkhard, Stephan Brand, Wolf, C., Maria Weidinger, Brand, S., Czamara, Darina, Jürgen Glas, Tillack Cornelia, Wolf Christiane, Lass, Ulrich, Czamara Darina, Lohse, Peter, Diegelmann, Julia, Simone Pfennig, Glas Jürgen, Torsten Olszak, Olszak, T., Florian Beigel, Lohse Peter, Julia Seiderer, Olszak, Torsten, Tillack, C.   +67 more
core   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, Accepted Article.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the CARRA, SPARTAN, and PRCSG Advisory Council   +9 more
wiley   +1 more source

Local Interactions Between Innate Immune Signaling, Microbiota, and Bile Acids Drive the Development of Duodenal AdenomasSummaryWhat You Need to Know

Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: Duodenal adenomas have malignant potential, yet the drivers of duodenal tumorigenesis remain unclear. Duodenal adenomas robustly develop in villin- Toll-like receptor 4 (TLR4) mice, a transgenic mouse model of increased innate ...
Juan F. Burgueño, Hajar Hazime, Julia Fritsch, Gillian E. Jacobsen, Henry D. Dione, Trevor Cickovski, Eddy E. González, Ana M. Santander, Irina Fernández, Nivis Brito, Zhen Gao, Yuguang Ban, Lily Wang, Landon Wilson, Stephen Barnes, Judith Pignac-Kobinger, Mark S. Sundrud, Maria T. Abreu   +17 more
doaj   +1 more source

Adenocarcinoma arising from chronic perianal crohn's disease: a case report

The Pan African Medical Journal, 2015
Malignant transformation of perineal fistula in Crohn's disease has rarely been reported. We report a case of Crohn's disease with recurrent perineal fistulas.
Hanane Massit, Meryem Edderai, Rachida Saouab, Hassan Seddik, Jamal El Fenni, Ahmed Benkirane   +5 more
doaj   +1 more source