Results 21 to 30 of about 102,860 (309)

Alterations of the CARD15/NOD2 gene and the impact on management and treatment of Crohn's disease patients [PDF]

, 2003
The recent identification of the CARD15/NOD2 gene as a susceptibility locus for Crohn's disease represents an important step towards the delineation of the immuno-pathogenesis of inflammatory bowel disease.
Folwaczny, Christian, Török, H. P., Lohse, P., Glas, J.   +3 more
core   +1 more source

Predicting outcome in Crohn’s disease [PDF]

, 2020
Crohn’s disease is a chronic immune-mediated disease which can cause inflammation in the gastrointestinal tract anywhere between mouth and anus. It is now understood to be the result of a complex interplay between genetic, microbial and environmental
Kennedy, Nicholas A.
core   +1 more source

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. [PDF]

, 2007
The IL23R gene has been identified as a susceptibility gene for inflammatory bowel disease (IBD) in the North American population. The aim of our study was to test this association in a large German IBD cohort and to elucidate potential interactions with
Folwaczny, Christian, Seiderer Julia, Ochsenkühn, Thomas, Klein, Wolfram, Griga Thomas, Schiemann Uwe, Folwaczny Matthias, Tonenchi, Laurian, Matthias Folwaczny, Bertram Müller-Myhsok, Schmechel, Silke, Jörg T Epplen, Epplen Jörg T., Jörg T. Epplen, Mussack, Thomas, Schiemann, Uwe, Pfennig Simone, Kerstin Maier, Brand, Stephan, Brand Stephan, Thomas Ochsenkühn, Török, Helga-Paula, Epplen, Jörg T., Thomas Griga, Konrad, Astrid, Müller-Myhsok Bertram, Astrid Konrad, Göke, Burkhard, Konrad Astrid, Wetzke Martin, Schmechel Silke, Epplen, Jörg T, Griga, Thomas, Folwaczny, Matthias, Pfennig, Simone, Peter Lohse, Folwaczny Christian, Seiderer, Julia, Török Helga-Paula, Julia Dambacher, Uwe Schiemann, Glas, Jürgen, Mussack Thomas, Silke Schmechel, Ochsenkühn Thomas, Grassl, Christine, Müller-Myhsok, Bertram, Tonenchi Laurian, Christian Folwaczny, Martin Wetzke, Dambacher Julia, Burkhard Göke, Helga-Paula Török, Göke Burkhard, Stephan Brand, Maier Kerstin, Dambacher, Julia, Jürgen Glas, Maier, Kerstin, Klein Wolfram, Wetzke, Martin, Laurian Tonenchi, Christine Grassl, Lohse, Peter, Thomas Mussack, Simone Pfennig, Wolfram Klein, Glas Jürgen, Lohse Peter, Julia Seiderer, Grassl Christine   +70 more
core   +1 more source

Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value [PDF]

, 2002
Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis
Török, H.-P., Hoelscher, Michael, Folwaczny, Christian, Vilsmaier, F., Herbinger, K. H., Glas, J.   +5 more
core   +1 more source

Radiologic images of complications of Crohn's disease

International Journal of Gastrointestinal Intervention, 2023
Crohn's disease is a chronic inflammatory disease that may occur in the alimentary tract and has various clinical courses. It is characterized by several complications, including bowel strictures, bowel obstruction, fistulas, abscesses, and ...
Sungjin Yoon, So Hyun Park, Jun Seong Kim   +2 more
doaj   +1 more source

Microscopic features of small bowel mucosa of patients with Crohn’s disease

BMC Gastroenterology, 2019
Background Double-balloon enteroscopy enables performing numerous small bowel biopsies for pathologic analysis. However, most histopathological characteristics of Crohn’s disease are non-specific characteristics.
Yun Cui, Shi-yuan Lu, Jie Xu, Yan-shen Peng, Qi Miao, Xiao-qing Wang, Xiao-yu Chen, Zhi-hua Ran   +7 more
doaj   +1 more source

Whole-exome sequencing in a subject with fluctuating neuropsychiatric symptoms, immunoglobulin G1 deficiency, and subsequent development of Crohn’s disease: a case report

Journal of Medical Case Reports, 2022
Background Mutations or polymorphisms of genes that are associated with inflammasome functions are known to predispose individuals to Crohn’s disease and likely affect clinical presentations and responses to therapeutic agents in patients with Crohn’s ...
Harumi Jyonouchi, Lee Geng
doaj   +1 more source

Clinical trials and young adults with inflammatory bowel disease

Health Care Transitions
Young adults (approximately 18–35 years) with inflammatory bowel disease (IBD) represent a distinct demographic with unique developmental and physiological characteristics, yet they are underrepresented in clinical trials.
Sneha Dave, Sydney Reed, Mara Shapiro, Yeabsira Taye, Isabela Hernandez, Navin Kariyawasam, Ildiko Mehes, Manasi Agrawal, Miguel Regueiro, Adam Faye, Jeremy Adler   +10 more
doaj   +1 more source

Multicentric Cutaneous Crohn's Disease: A Case Report and Review of Literature

Canadian Journal of Gastroenterology, 1990
A patient presented with skin lesions at sites not contiguous with Crohn's disease of the bowel and with specific histological features of Crohn's disease occurring two weeks from the onset of bowel symptoms.
Robert Prokopetz, J Barrie Ross, Peter Smith, Joseph J Sidorov   +3 more
doaj   +1 more source

Where are all the Mycobacterium avium subspecies paratuberculosis in patients with Crohn's disease?

PLoS Pathogens, 2009
Mycobacterium avium subspecies paratuberculosis (MAP) causes a chronic granulomatous inflammation of the intestines, Johne's disease, in dairy cows and every other species of mammal in which it has been identified.
Ellen S Pierce
doaj   +1 more source