Azathioprine and 6-mercaptopurine for maintenance of surgically-induced remission in Crohn’s disease [PDF]
, 2014 Background Crohn’s disease (CD) is a chronic relapsing inflammatory condition. Many patients fail to achieve remission with medical management and require surgical interventions.
Angelberger +41 more
core +1 more source
Progress and Clinical Applications of Crohn’s Disease Exclusion Diet in Crohn’s Disease
Gut and LiverCrohn’s disease is a chronic intestinal inflammatory disorder of unknown etiology. Although the pharmacotherapies for Crohn’s disease are constantly updating, nutritional support and adjuvant therapies have recently gained more attention.
Duo Xu +5 more
doaj +1 more source
How mucosal epithelia deal with stress: Role of NKG2D/NKG2D ligands during inflammation [PDF]
, 2017 Mucosal epithelia encounter both physicochemical and biological stress during their life and have evolved several mechanisms to deal with them, including regulation of immune cell functions.
Alessandra Soriani +5 more
core +2 more sources
Pulmonary Extraintestinal Manifestation of Crohn’s Disease Treated Successfully with Adalimumab
The Korean Journal of Gastroenterology, 2018 Pulmonary extraintestinal manifestation is rare in Crohn’s disease and has been reported in only a few cases. Despite the presence of pulmonary abnormalities in a significant proportion of patients with inflammatory bowel disease, there are only few case
Dongyeol Shin +6 more
doaj +1 more source
Metastatic Crohn’s disease despite infliximab therapy [PDF]
Anais Brasileiros de Dermatologia, 2017 Metastatic Crohn’s disease is a rare extraintestinal manifestation of Crohn’s disease. It is characterized by polymorphic skin lesions formed by non-caseating granulomas located on anatomical sites distant from the gastrointestinal tract.
Sara Campos +3 more
doaj +1 more source
Epigenetic silencing of SOCS3 expression contributes to fibrosis in Crohn’s disease [PDF]
, 2017 Identified risk polymorphisms affecting the Jak-STAT3 pathway in patients with Crohn’s disease could affect TGF-β1 and collagen I expression and in the pathway’s negative regulator, SOCS3.
Kuemmerle, John F +2 more
core +1 more source
Influence of Crohn’s disease related polymorphisms in innate immune function on ileal microbiome [PDF]
, 2019 We have previously identified NOD2 genotype and inflammatory bowel diseases (IBD) phenotype, as associated with shifts in the ileal microbiome (“dysbiosis”) in a patient cohort.
Ciorba, Matthew A +13 more
core +3 more sources
Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source
The feasibility of wireless capsule endoscopy in detecting small intestinal pathology in children under the age of 8 years: a multicentre European study. [PDF]
, 2009 Objective: To systematically evaluate the feasibility and methodology to carry out wireless capsule endoscopy (WCE) in children
Bufler, Philip +8 more
core +3 more sources
Additional file 2: of Identifying Crohnâ s disease signal from variome analysis
, 2019 Supplementary methods and results. (PDF 4720 kb)
Yanran Wang +6 more
openaire +1 more source