Results 91 to 100 of about 9,352,293 (347)
Dermatology Online Journal, 2006 Crohn disease is a chronic inflammatory disease characterized by sharply demarcated segments of gastrointestinal involvement from mouth to anus. Its perineal manifestations are among the most devastating and mutilating complications. They occur at any time and may precede the intestinal manifestations.
Asma, Sioud Dhrif +4 more
openaire +4 more sources
RORγt‐APCs: The New Masters of Oral Tolerance
Barrier Immunity, EarlyView.ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source
An evidence-based review of natalizumab therapy in the management of Crohn’s disease
Therapeutics and Clinical Risk Management, 2009 Raja GR Edula, Michael F PiccoMayo Clinic, Jacksonville, Florida, USAAbstract: Treatment options for Crohn’s disease have evolved beyond the early goals of induction and remission and are now more focused on preventing complications by altering
Raja GR Edula, Michael F Picco
doaj
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Epilepsia Open, EarlyView.Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source
Duodenal Crohn’s Disease [PDF]
Inflammatory Bowel Diseases, 2018 Symptomatic duodenal Crohn's disease (CD) is an uncommon disease presentation, especially in isolation. The most common duodenal disease phenotype is stricturing disease rather than inflammatory or perforating. Most patients are asymptomatic and are therefore diagnosed incidentally by cross-sectional imaging or endoscopy.
openaire +2 more sources
Food Frontiers, EarlyView.Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh +11 more
wiley +1 more source
Food Frontiers, EarlyView.CMTR‐Gel targeting to the inflamed mucosa by electrostatic interactions. ABSTRACT Natural drug‐food homology compounds have vast therapeutic potential, particularly for inflammatory bowel disease (IBD), but their poor water solubility, instability, and limited mucosal availability hinder their clinical translation.
Wenqiu Xu +7 more
wiley +1 more source
Transperineal Ultrasonography in Perianal Crohn Disease: A Valuable Imaging Modality
Canadian Journal of Gastroenterology and Hepatology, 2015 Aims of treatment for Crohn disease have moved beyond the resolution of clinical symptoms to objective end points including endoscopic and radiological normality. Regular re-evaluation of disease status to safely, readily and reliably detect the presence
Emily K Wright +5 more
doaj +1 more source
Early bronchopulmonary involvement in Crohn disease: a case report
BMC Gastroenterology, 2001 Background Bronchopulmonary manifestations of Crohn disease have been rarely described in children, including both subclinical pulmonary involvement and severe lung disease.
Braggion Cesare +5 more
doaj +1 more source
Anais Brasileiros de Dermatologia, 2009 Os autores relatam caso de paciente feminina de 47 anos, com lesões cutâneas ulceradas, disseminadas, iniciadas sete anos antes do acompanhamento. Os achados histopatológicos de tais lesões, somados aos endoscópicos, permitiram o diagnóstico de uma ...
Marcelo D’Ambrosio Fernandes +4 more
doaj +1 more source