Results 91 to 100 of about 62,187 (355)
The Saudi Journal of Gastroenterology, 2009 Distinguishing tuberculosis and Crohn′s disease in patients presenting with chronic abdominal pain and diarrhea is a huge diagnostic challenge, particularly in tuberculosis endemic countries.
Navaneethan Udayakumar +3 more
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Immunotherapy of Crohn′s disease
Mediators of Inflammation, 1998 Although the initiating events of Crohn′s disease are unknown, models of experimental colitis have provided new insights in the immunologically mediated pathways of mucosal inflammation. In Crohn′s disease activated mucosal T lymphocytes produce proinflammatory cytokines within the mucosal compartment. With this understanding, there has been a shift in
van Montfrans, C. +2 more
openaire +6 more sources
Clinical Pharmacology &Therapeutics, EarlyView.Physiologically Motivated Sequential Population Modeling of Albumin Trends and Vedolizumab Pharmacokinetics for Pregnancy Dosing Regimen Optimization. The pharmacokinetics (PK) of monoclonal antibodies (mAbs) during pregnancy remains poorly characterized, despite active inflammatory bowel diseases (IBD) being the greatest risk factor for adverse ...
Zrinka Duvnjak +8 more
wiley +1 more source
Perianal Crohn's disease: challenges and solutions
Clinical and Experimental Gastroenterology, 2017 Katherine A Kelley, Taranjeet Kaur, Vassiliki L Tsikitis Department of General Surgery, Division of Gastrointestinal and General Surgery, Oregon Health and Sciences University, Portland, OR, USA Abstract: Perianal Crohn’s disease ...
Kelley KA, Kaur T, Tsikitis VL
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Clinical features of nonspecific ulcerative colitis and Crohn's disease in children [PDF]
Саратовский научно-медицинский журнал, 2010 The article presents the data of age, manifestation, localization and clinical features of course of Crohn's disease and nonspecific ulcerative colitis.
Malakhinova N.A.
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Vulvar Crohn´s disease as extra intestinal manifestation
The Pan African Medical Journal, 2020 Crohn´s disease is a chronic granulomatous inflammatory disorder that usually affects the gastrointestinal tract. It may be associated with extra-intestinal lesions such as genital female manifestations.
Fatima El Mangoub, Jaouad Kouach
doaj +1 more source
Intestinal Barrier Glycosylation for Gut Physiology and Pathology
Barrier Immunity, EarlyView.ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley +1 more source
Metastatic Crohn′s disease of external genitalia
Indian Journal of Dermatology, 2008 Metastatic Crohn′s disease is an uncommon extraintestinal manifestation of Crohn′s disease. Its hallmark features include the presence of cutaneous noncaseating granulomas that are noncontiguous with the gastrointestinal tract or fistula ...
Panackel Charles +3 more
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Dual Biologic Therapy in a Patient With Niemann‐Pick Type C and Crohn Disease
, 2022 Alexandra Hudson +2 more
openalex +1 more source
RORγt‐APCs: The New Masters of Oral Tolerance
Barrier Immunity, EarlyView.ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source