Results 91 to 100 of about 59,318 (349)
Arthritis &Rheumatology, EarlyView.Objective JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but Tyk2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn disease, which highlights the complex role for JAK/STAT signaling in different inflammatory processes.
Sami Giryes +14 more
wiley +1 more source
The Saudi Journal of Gastroenterology, 2009 Distinguishing tuberculosis and Crohn′s disease in patients presenting with chronic abdominal pain and diarrhea is a huge diagnostic challenge, particularly in tuberculosis endemic countries.
Navaneethan Udayakumar +3 more
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Clinical features of nonspecific ulcerative colitis and Crohn's disease in children [PDF]
Саратовский научно-медицинский журнал, 2010 The article presents the data of age, manifestation, localization and clinical features of course of Crohn's disease and nonspecific ulcerative colitis.
Malakhinova N.A.
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Clinical and Translational Gastroenterology, 2017 Fistulas still represent one of the most important complications in patients with Crohn's disease (CD). At least one third of CD patients suffer from fistulas during their disease course and amongst them longstanding remission of complex fistulas occurs only in about one third. So far, fistula pathogenesis is only partially understood.
Scharl, Michael +2 more
openaire +3 more sources
Arthritis &Rheumatology, Accepted Article.Objective Despite availability of biologics and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) to treat rheumatoid arthritis (RA), many patients do not experience optimized disease control. Glucocorticoids are effective but have safety risks.
Frank Buttgereit +13 more
wiley +1 more source
Metastatic Crohn′s disease of external genitalia
Indian Journal of Dermatology, 2008 Metastatic Crohn′s disease is an uncommon extraintestinal manifestation of Crohn′s disease. Its hallmark features include the presence of cutaneous noncaseating granulomas that are noncontiguous with the gastrointestinal tract or fistula ...
Panackel Charles +3 more
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Alterations of the CARD15/NOD2 gene and the impact on management and treatment of Crohn's disease patients [PDF]
, 2003 The recent identification of the CARD15/NOD2 gene as a susceptibility locus for Crohn's disease represents an important step towards the delineation of the immuno-pathogenesis of inflammatory bowel disease.
Folwaczny, Christian +3 more
core +1 more source
Clonal sharing of CD8+ T‐cells links skin and joint inflammation in psoriatic arthritis
Arthritis &Rheumatology, Accepted Article.Objective Psoriatic arthritis (PsA) is an HLA class I‐associated inflammatory arthritis that develops in up to 30% of people with psoriasis. We tested the hypothesis that skin and joint inflammation in PsA is linked in terms of CD8+ T‐cell phenotype and clonality.
Lucy E. Durham +14 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Amgevita is a licensed biosimilar to adalimumab, having demonstrated high pharmacokinetic and clinical similarity to Humira. Switching to a lower‐cost medicine may elicit a nocebo effect, whereby expectations of poorer efficacy impact outcomes despite pharmacological similarity. This prospective cohort study examined clinical and economic outcomes
Louise Rabbitt +7 more
wiley +1 more source
Perianal Crohn's disease: challenges and solutions
Clinical and Experimental Gastroenterology, 2017 Katherine A Kelley, Taranjeet Kaur, Vassiliki L Tsikitis Department of General Surgery, Division of Gastrointestinal and General Surgery, Oregon Health and Sciences University, Portland, OR, USA Abstract: Perianal Crohn’s disease ...
Kelley KA, Kaur T, Tsikitis VL
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