Results 71 to 80 of about 24,256 (259)

Perianal Crohn's disease: challenges and solutions

open access: yesClinical and Experimental Gastroenterology, 2017
Katherine A Kelley, Taranjeet Kaur, Vassiliki L Tsikitis Department of General Surgery, Division of Gastrointestinal and General Surgery, Oregon Health and Sciences University, Portland, OR, USA Abstract: Perianal Crohn’s disease ...
Kelley KA, Kaur T, Tsikitis VL
doaj  

Clinical features of nonspecific ulcerative colitis and Crohn's disease in children [PDF]

open access: yesСаратовский научно-медицинский журнал, 2010
The article presents the data of age, manifestation, localization and clinical features of course of Crohn's disease and nonspecific ulcerative colitis.
Malakhinova N.A.
doaj  

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu   +3 more
wiley   +1 more source

Metastatic Crohn′s disease of external genitalia

open access: yesIndian Journal of Dermatology, 2008
Metastatic Crohn′s disease is an uncommon extraintestinal manifestation of Crohn′s disease. Its hallmark features include the presence of cutaneous noncaseating granulomas that are noncontiguous with the gastrointestinal tract or fistula ...
Panackel Charles   +3 more
doaj  

Simultaneous central retinal artery occlusion and optic nerve vasculitis in Crohn disease

open access: yesAmerican Journal of Ophthalmology Case Reports, 2017
Purpose: To describe a case of Crohn disease presenting as occlusive vasculitis resulting in a central retinal artery occlusion (CRAO) in one eye and transient ischemic optic neuropathy in the fellow eye.
Razek Georges Coussa   +4 more
doaj   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

open access: yesBMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang   +13 more
wiley   +1 more source

Radiologic, Histologic and Scanning Electron Microscopic Characterization of the Peritoneal Reflection in Crohn's Disease

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The peritoneal reflection bridges visceral and parietal peritoneum and lacks adjoining or underlying organs. As such it provides an opportunity to perform a focussed examination of the peritoneum in Crohn's disease. The aim of this study was to exploit this anatomical property and conduct a multilayered, focussed examination of the peritoneal ...
L. Walsh   +4 more
wiley   +1 more source

An evidence-based review of natalizumab therapy in the management of Crohn’s disease

open access: yesTherapeutics and Clinical Risk Management, 2009
Raja GR Edula, Michael F PiccoMayo Clinic, Jacksonville, Florida, USAAbstract: Treatment options for Crohn’s disease have evolved beyond the early goals of induction and remission and are now more focused on preventing complications by altering
Raja GR Edula, Michael F Picco
doaj  

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor   +12 more
wiley   +1 more source

Crohn's disease in women.

open access: yesInternational journal of women's health, 2013
This article provides an overview of the obstetric and gynecological manifestations of Crohn's disease (CD). High incidence of the new onset of the disease in young women in their reproductive years demands special concern from physicians involved in their treatment.
Plavšić, Ivana   +2 more
openaire   +4 more sources

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