Results 121 to 130 of about 59,318 (349)

Next generation of biologics for the treatment of Crohn’s disease: an evidence-based review on ustekinumab

Clinical and Experimental Gastroenterology, 2017
Aranzazu Jauregui-Amezaga, Michael Somers, Heiko De Schepper, Elisabeth Macken Department of Gastroenterology, Universitair Ziekenhuis Antwerpen, University of Antwerp, Antwerp, Belgium Abstract: The limited efficacy of the currently ...
Jauregui-Amezaga A, Somers M, De Schepper H, Macken E   +3 more
doaj  

Fragility Index analysis for robustness of evidence in Randomized Controlled Trials in National Comprehensive Cancer Network (NCCN) guidelines for rectal cancer

International Journal of Cancer, EarlyView.
What's New? Data from randomized controlled trials (RCTs) forms a foundation for rectal cancer treatment guidelines. The reliability of such data is therefore essential for evidence‐based clinical decision‐making. This study assessed the robustness of RCTs cited in the latest National Comprehensive Cancer Network (NCCN) guidelines for rectal cancer ...
Nir Horesh, Justin Dourado, Peter Rogers, Pauline Aeschbacher, Zoe Garoufalia, Rachel Gefen, Ebram Salama, Sameh Hany Emile, Steven D. Wexner   +8 more
wiley   +1 more source

The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [PDF]

, 2020
Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity.
Clark, Ashley K, Saric-Bosanac, Suzana, Shi, Vivian Y, Sivamani, Raja K   +3 more
core  

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

Computed tomography enterography and magnetic resonance enterography in small intestine of Crohn's disease

Journal of Coloproctology, 2017
Crohn disease is defined as a chronic inflammatory and idiopathic process that can affect any portion of the gastrointestinal tract. The small intestine is the most frequently affected place, so small bowel morphology investigation is often mandatory.For
Aida Cristina Correia Oliveira Azevedo, Sandra Fátima Fernandes Martins   +1 more
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Pellagra as the initial presentation of Crohn disease [PDF]

, 2012
Pellagra is a nutritional disease caused by the deficiency of niacin. We describe a case of pellagra as the initial presentation of Crohn disease, which has been rarely described in the ...
Fernandes, I., Oliveira, A., Pinto-Almeida, T., Rosmaninho, A., Sanches, M., Selores, M., Vilaça, S.   +6 more
core   +1 more source

Electroacupuncture reshapes the microbial co‐occurrence networks related to the behavioral and psychological symptoms of dementia in Alzheimer's disease

iMetaOmics, EarlyView.
Microbial keystone species and gut microbiota composition are highly variable during the pathological development of the behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease (AD). Age stratification reveals stage‐specific gut microbial signatures in AD‐related BPSD.
Fu‐You Su, Chia‐Min Lin, Chao Liu, Yiqin Yao, Hui Wang, Chunxue Zhang, Wei Yi, Nenggui Xu   +7 more
wiley   +1 more source

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

Interdisciplinary Medicine, EarlyView.
This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao, Zheng‐ting Wu, Qi You, Yuan‐yuan Xia, Qing Zhao, Carine de Marcos Lousa, Ke‐wei Zhao   +6 more
wiley   +1 more source

Leveraging interprofessional team‐based care in an IBD clinic to transition patients from intravenous to subcutaneous risankizumab‐rzaa

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, EarlyView.
Abstract There are no data evaluating the success rate in transitioning intravenous (IV) to subcutaneous (SQ) risankizumab‐rzaa. To address these challenges, the University of Chicago Medicine (UCM) utilized an interprofessional team‐based, pharmacist‐directed follow‐up strategy to ensure patients initiate and maintain therapy.
David Choi, Marita Kametas, Jacqueline Gianni, Justin Han, David T. Rubin   +4 more
wiley   +1 more source

Medical treatment of perianal crohn disease

The Saudi Journal of Gastroenterology, 2002
Crohn disease is a chronic illness that affects the gastrointestinal tract from the mouth to the anus. Perianal Crohn develops in 31-94% of patients over the course of their illness. It affects the skin in the perianal area, the anal canal and can
Al-Ghamdi Abdullah
doaj