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Strategies and methods of medical therapy for refractory Crohn's disease [PDF]

Yixue xinzhi zazhi, 2022
Crohn's disease (CD) is an inflammatory bowel disease that can affect the entire digestive tract. Although new drugs have been introduced in recent years, there are still some patients who are unresponsive to various treatments.
Qiao ZHONG, A-Kang SHAO, Min CHEN
doaj   +1 more source

The Medical Management of Paediatric Crohn's Disease: an ECCO-ESPGHAN Guideline Update.

Journal of Crohn's & Colitis, 2020
OBJECTIVE We aimed to provide an evidence-supported update of the ECCO-ESPGHAN guideline on the medical management of paediatric Crohn's disease [CD]. METHODS We formed 10 working groups and formulated 17 PICO-structured clinical questions [Patients ...
P. V. van Rheenen, M. Aloi, A. Assa, J. Bronský, J. Escher, U. Fagerberg, M. Gasparetto, K. Gerasimidis, A. Griffiths, P. Henderson, S. Koletzko, K. Kolho, A. Levine, J. V. van Limbergen, F. J. Martín de Carpi, V. Navas-López, S. Oliva, L. de Ridder, R. Russell, D. Shouval, A. Spinelli, D. Turner, D. Wilson, E. Wine, F. Ruemmele   +24 more
semanticscholar   +1 more source

Clostridium difficile infection in a patient with Crohn disease

Journal of the Formosan Medical Association, 2012
Crohn disease is a chronic inflammatory disorder, which is rare in pediatric patients. The definite etiology and mechanism to induce an acute exacerbation of Crohn disease remains mostly unknown.
Chien-Hui Hsu, Yung-Ming Jeng, Yen-Hsuan Ni   +2 more
doaj   +1 more source

Research progress in the surgical treatment of anorectal stricture in Crohn disease [PDF]

Yixue xinzhi zazhi, 2023
Anorectal stricture is the most challenging complication of perianal Crohn disease, and it often has a severe negative impact on the patient's quality of life.
Jin-Rong LI, Li-Bei ZHU, Ze-Peng CHEN, Li-Chao QIAO, Yu-Xia GONG, Bai-Lin YANG, Ping ZHU   +6 more
doaj   +1 more source

Opioid use is associated with decreased quality of life in patients with Crohn′s disease

The Saudi Journal of Gastroenterology, 2014
Background/Aims: Quality of life is an important consideration in the management of patients with Crohn′s disease. Previous studies suggest that Crohn′s disease patients using opioids may have decreased quality of life and increased risk of mortality ...
David Sanford, Patrick Thornley, Anouar Teriaky, Nilesh Chande, James Gregor   +4 more
doaj   +1 more source

Leukocytoclastic Vasculitis in a Patient With Crohn Disease: A Case Report

Journal of Investigative Medicine High Impact Case Reports, 2023
Leukocytoclastic vasculitis (LCV) is an idiopathic small vessel vasculitis. Leukocytoclastic vasculitis can be found in a spectrum of diseases and is noted as a rare extraintestinal manifestation of Crohn disease.
Mark Daniele Bugada BS, Vamsi K. Emani MD   +1 more
doaj   +1 more source

Crohn's disease

The Lancet, 2012
Crohn's disease is a relapsing systemic inflammatory disease, mainly affecting the gastrointestinal tract with extraintestinal manifestations and associated immune disorders. Genome wide association studies identified susceptibility loci that--triggered by environmental factors--result in a disturbed innate (ie, disturbed intestinal barrier, Paneth ...
Baumgart, Daniel C, Sandborn, William J
openaire   +2 more sources

Patient-derived Colonoids From Disease-spared Tissue Retain Inflammatory Bowel Disease-specific Transcriptomic Signatures

Gastro Hep Advances, 2023
Background and Aims: A key histopathological feature of inflammatory bowel disease is damage to the mucosa, including breakdown of the epithelial barrier.
Tatiana A. Karakasheva, Yusen Zhou, Hongbo M. Xie, Gloria E. Soto, Tiana D. Johnson, Madison A. Stoltz, Daana M. Roach, Noor Nema, Chizoba N. Umeweni, Kaitlyn Naughton, Lauren Dolinsky, James A. Pippin, Andrew D. Wells, Struan F.A. Grant, Louis Ghanem, Natalie Terry, Amanda B. Muir, Kathryn E. Hamilton   +17 more
doaj   +1 more source

Research progress on risk factors for anastomotic recurrence after Crohn disease [PDF]

Yixue xinzhi zazhi, 2023
Intestinal resection and reconstruction are crucial steps in surgical treatment for Crohn disease. However, anastomotic recurrence is a common complication following reconstruction surgery.
Bao-Jia YAO, Li-Chao YANG, Qiang WU, Gang-Lei LIU   +3 more
doaj   +1 more source

ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment.

Journal of Crohn's & Colitis, 2019
This article is the second in a series of two publications relating to the European Crohn's and Colitis Organisation [ECCO] evidence-based consensus on the management of Crohn's disease.
M. Adamina, S. Bonovas, T. Raine, A. Spinelli, J. Warusavitarne, A. Armuzzi, O. Bachmann, P. Bager, L. Biancone, B. Bokemeyer, P. Bossuyt, J. Burisch, P. Collins, G. Doherty, A. El‐Hussuna, P. Ellul, G. Fiorino, C. Frei-Lanter, F. Furfaro, C. Gingert, P. Gionchetti, J. Gisbert, F. Gomollón, Marien González Lorenzo, H. Gordon, T. Hlavatý, P. Juillerat, K. Katsanos, U. Kopylov, E. Krustiņš, T. Kucharzik, T. Lytras, C. Maaser, F. Magro, J. K. Marshall, P. Myrelid, Gianluca Pellino, I. Rosa, J. Sabino, E. Savarino, L. Stassen, J. Torres, Mathieu Uzzan, S. Vavricka, B. Verstockt, O. Zmora   +45 more
semanticscholar   +1 more source