Results 21 to 30 of about 4,849,663 (241)

Clostridium difficile infection in a patient with Crohn disease

open access: yesJournal of the Formosan Medical Association, 2012
Crohn disease is a chronic inflammatory disorder, which is rare in pediatric patients. The definite etiology and mechanism to induce an acute exacerbation of Crohn disease remains mostly unknown.
Chien-Hui Hsu   +2 more
doaj   +1 more source

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. [PDF]

open access: yes, 2007
The IL23R gene has been identified as a susceptibility gene for inflammatory bowel disease (IBD) in the North American population. The aim of our study was to test this association in a large German IBD cohort and to elucidate potential interactions with
Folwaczny, Christian   +70 more
core   +2 more sources

Opioid use is associated with decreased quality of life in patients with Crohn′s disease

open access: yesThe Saudi Journal of Gastroenterology, 2014
Background/Aims: Quality of life is an important consideration in the management of patients with Crohn′s disease. Previous studies suggest that Crohn′s disease patients using opioids may have decreased quality of life and increased risk of mortality ...
David Sanford   +4 more
doaj   +1 more source

Clinical presentation of Crohn's disease. Association between familial disease, smoking, disease phenotype, extraintestinal manifestations and need for surgery [PDF]

open access: yes, 2005
Background/Aims: Recent molecular data suggest that genetic factors may underlie the disease heterogeneity observed in Crohn's disease (CD). It was also suggested that familial inflammatory bowel disease (IBD) is a homogenous subgroup, phenotypically ...
Gasztonyi, Beáta   +16 more
core   +2 more sources

Research progress in the surgical treatment of anorectal stricture in Crohn disease [PDF]

open access: yesYixue xinzhi zazhi, 2023
Anorectal stricture is the most challenging complication of perianal Crohn disease, and it often has a severe negative impact on the patient's quality of life.
Jin-Rong LI   +6 more
doaj   +1 more source

PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background. [PDF]

open access: yes, 2012
Genome-wide association studies identified PTPN2 (protein tyrosine phosphatase, non-receptor type 2) as susceptibility gene for inflammatory bowel diseases (IBD).
Darina Czamara   +63 more
core   +2 more sources

Leukocytoclastic Vasculitis in a Patient With Crohn Disease: A Case Report

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2023
Leukocytoclastic vasculitis (LCV) is an idiopathic small vessel vasculitis. Leukocytoclastic vasculitis can be found in a spectrum of diseases and is noted as a rare extraintestinal manifestation of Crohn disease.
Mark Daniele Bugada BS   +1 more
doaj   +1 more source

Crohn's disease activity index and Vienna classification - Is it worthwhile to calculate before surgery? [PDF]

open access: yes, 2006
Background: Crohn's disease (CD) patients with increased disease activity may reveal an increased risk for perioperative complications. The `Crohn's disease activity index' (CDAI) and the `Vienna classification' (VC) were developed for standardized ...
Jauch, Karl-Walter   +5 more
core   +1 more source

Strategies and methods of medical therapy for refractory Crohn's disease [PDF]

open access: yesYixue xinzhi zazhi, 2022
Crohn's disease (CD) is an inflammatory bowel disease that can affect the entire digestive tract. Although new drugs have been introduced in recent years, there are still some patients who are unresponsive to various treatments.
Qiao ZHONG, A-Kang SHAO, Min CHEN
doaj   +1 more source

Patient-derived Colonoids From Disease-spared Tissue Retain Inflammatory Bowel Disease-specific Transcriptomic Signatures

open access: yesGastro Hep Advances, 2023
Background and Aims: A key histopathological feature of inflammatory bowel disease is damage to the mucosa, including breakdown of the epithelial barrier.
Tatiana A. Karakasheva   +17 more
doaj   +1 more source

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