Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 Caucasian cohorts [PDF]
Background: DLG5 p. R30Q has been reported to be associated with Crohn disease ( CD), but this association has not been replicated in most studies. A recent analysis of gender-stratified data from two case-control studies and two population cohorts found
Vermeire, S +151 more
core +1 more source
Cows Get Crohn’s Disease and They’re Giving Us Diabetes
Increasingly, Johne’s disease of ruminants and human Crohn’s disease are regarded as the same infectious disease: paratuberculosis. Mycobacterium avium ss.
Coad Thomas Dow, Leonardo A Sechi
doaj +1 more source
Crohn disease is associated with nonnecrotizing epithelioid granulomas, which rarely involve extra-intestinal solid organs. Management of moderate-to-severe Crohn disease, especially with extra-intestinal manifestations, relies on biologic therapies and ...
Collin Mayemura +5 more
doaj +1 more source
Opioid use is associated with decreased quality of life in patients with Crohn′s disease
Background/Aims: Quality of life is an important consideration in the management of patients with Crohn′s disease. Previous studies suggest that Crohn′s disease patients using opioids may have decreased quality of life and increased risk of mortality ...
David Sanford +4 more
doaj +1 more source
Research progress in the surgical treatment of anorectal stricture in Crohn disease [PDF]
Anorectal stricture is the most challenging complication of perianal Crohn disease, and it often has a severe negative impact on the patient's quality of life.
Jin-Rong LI +6 more
doaj +1 more source
rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. [PDF]
The IL23R gene has been identified as a susceptibility gene for inflammatory bowel disease (IBD) in the North American population. The aim of our study was to test this association in a large German IBD cohort and to elucidate potential interactions with
Folwaczny, Christian +70 more
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Strategies and methods of medical therapy for refractory Crohn's disease [PDF]
Crohn's disease (CD) is an inflammatory bowel disease that can affect the entire digestive tract. Although new drugs have been introduced in recent years, there are still some patients who are unresponsive to various treatments.
Qiao ZHONG, A-Kang SHAO, Min CHEN
doaj +1 more source
Crohn's disease activity index and Vienna classification - Is it worthwhile to calculate before surgery? [PDF]
Background: Crohn's disease (CD) patients with increased disease activity may reveal an increased risk for perioperative complications. The `Crohn's disease activity index' (CDAI) and the `Vienna classification' (VC) were developed for standardized ...
Jauch, Karl-Walter +5 more
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Ligneous conjunctivitis in a patient with Crohn′s disease
Graciana Fuentes-Páez1, José M Herreras1, M del C Méndez2, MA Saorni1,21Ocular Immunology and Uveitis Unit, Institute of Ophthalmobiology (IOBA), University of Valladolid, Valladolid, Spain and Hospital Universitario de ...
Graciana Fuentes-Páez +3 more
doaj +1 more source
PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background. [PDF]
Genome-wide association studies identified PTPN2 (protein tyrosine phosphatase, non-receptor type 2) as susceptibility gene for inflammatory bowel diseases (IBD).
Darina Czamara +63 more
core +1 more source

