Metagenomic Analysis of the Structure and Function of the Human Gut Microbiota in Crohn's Disease [PDF]
, 2010 Inflammatory bowel diseases (IBD), such as Crohn’s disease, are chronic, immunologically mediated disorders that have severe medical consequences.
Claire M. Fraser-Liggett
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Cows Get Crohn’s Disease and They’re Giving Us Diabetes
Microorganisms, 2019 Increasingly, Johne’s disease of ruminants and human Crohn’s disease are regarded as the same infectious disease: paratuberculosis. Mycobacterium avium ss.
Coad Thomas Dow, Leonardo A Sechi
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Annals of Internal Medicine: Clinical Cases, 2023 Crohn disease is associated with nonnecrotizing epithelioid granulomas, which rarely involve extra-intestinal solid organs. Management of moderate-to-severe Crohn disease, especially with extra-intestinal manifestations, relies on biologic therapies and ...
Collin Mayemura +5 more
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Clostridium difficile infection in a patient with Crohn disease
Journal of the Formosan Medical Association, 2012 Crohn disease is a chronic inflammatory disorder, which is rare in pediatric patients. The definite etiology and mechanism to induce an acute exacerbation of Crohn disease remains mostly unknown.
Chien-Hui Hsu +2 more
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Higher risk of tuberculosis reactivation when anti-TNF is combined with immunosuppressive agents. A systematic review of randomized controlled trials [PDF]
, 2014 Objective. Treatment with tumour necrosis factor antagonists (anti-TNF) has been recognized as a risk factor for tuberculosis (TB) reactivation. Our aim was to evaluate risk of TB reactivation in rheumatologic and non-rheumatologic diseases treated with ...
Armuzzi, Alessandro +9 more
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Opioid use is associated with decreased quality of life in patients with Crohn′s disease
The Saudi Journal of Gastroenterology, 2014 Background/Aims: Quality of life is an important consideration in the management of patients with Crohn′s disease. Previous studies suggest that Crohn′s disease patients using opioids may have decreased quality of life and increased risk of mortality ...
David Sanford +4 more
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Research progress in the surgical treatment of anorectal stricture in Crohn disease [PDF]
Yixue xinzhi zazhi, 2023 Anorectal stricture is the most challenging complication of perianal Crohn disease, and it often has a severe negative impact on the patient's quality of life.
Jin-Rong LI +6 more
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The Lancet, 2012 Crohn's disease is a relapsing systemic inflammatory disease, mainly affecting the gastrointestinal tract with extraintestinal manifestations and associated immune disorders. Genome wide association studies identified susceptibility loci that--triggered by environmental factors--result in a disturbed innate (ie, disturbed intestinal barrier, Paneth ...
Baumgart, Daniel C, Sandborn, William J
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Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: Pathogenic bacteria and altered bacterial sensing or changes in mucosal integrity take "toll"? [PDF]
, 2006 The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various environmental and host (e.g. genetic-, epithelial-, immune and non-immune) factors are involved.
Fischer, Simon +4 more
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Strategies and methods of medical therapy for refractory Crohn's disease [PDF]
Yixue xinzhi zazhi, 2022 Crohn's disease (CD) is an inflammatory bowel disease that can affect the entire digestive tract. Although new drugs have been introduced in recent years, there are still some patients who are unresponsive to various treatments.
Qiao ZHONG, A-Kang SHAO, Min CHEN
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